APEH (gene)

APEH
Identifiers
Aliases	APEH, AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH, acylaminoacyl-peptide hydrolase
External IDs	OMIM: 102645; MGI: 88041; HomoloGene: 1240; GeneCards: APEH; OMA:APEH - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	49,683,971 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,971,805 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; anterior pituitary; ; muscle of thigh; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right adrenal gland; ; right adrenal cortex; ; apex of heart; ; left adrenal gland; ; left adrenal cortex;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; right kidney; ; human kidney; ; epithelium of small intestine; ; interventricular septum; ; duodenum; ; jejunum; ; left lobe of liver; ; spleen; ; intestinal villus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	omega peptidase activity; serine-type peptidase activity; protein binding; hydrolase activity; serine-type endopeptidase activity; identical protein binding; RNA binding;
Cellular component	nuclear membrane; extracellular exosome; extracellular region; cytoplasm; cytosol; ficolin-1-rich granule lumen;
Biological process	translational termination; amyloid-beta metabolic process; proteolysis; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	327
	235606
	ENSG00000164062
	ENSMUSG00000032590
	P13798
	Q8R146
	NM_001640
	NM_146226
	NP_001631
	NP_666338
	Wikidata
View/Edit Human	View/Edit Mouse

Acylamino-acid-releasing enzyme is an enzyme that in humans is encoded by the APEH gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164062 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032590 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Erlandsson R; Bergerheim US; Boldog F; Marcsek Z; Kunimi K; Lin BY; Ingvarsson S; Castresana JS; Lee WH (Oct 1990). "A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC)". Oncogene. 5 (8): 1207–11. PMID 2392324. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
^ "Entrez Gene: APEH N-acylaminoacyl-peptide hydrolase".