APOBEC3D

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Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
Identifiers
Symbols APOBEC3D ; A3D; APOBEC3DE; APOBEC3E; ARP6
External IDs OMIM609900 HomoloGene122788 GeneCards: APOBEC3D Gene
EC number 3.5.4.-
Orthologs
Species Human Mouse
Entrez 140564 n/a
Ensembl ENSG00000243811 n/a
UniProt Q96AK3 n/a
RefSeq (mRNA) NM_152426 n/a
RefSeq (protein) NP_689639 n/a
Location (UCSC) Chr 22:
39.41 – 39.43 Mb
n/a
PubMed search [1] n/a

Probable DNA dC->dU-editing enzyme APOBEC-3D is a protein that in humans is encoded by the APOBEC3D gene.[1][2]

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.[2]

References[edit]

  1. ^ Jarmuz A, Chester A, Bayliss J, Gisbourne J, Dunham I, Scott J, Navaratnam N (Feb 2002). "An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22". Genomics 79 (3): 285–96. doi:10.1006/geno.2002.6718. PMID 11863358. 
  2. ^ a b "Entrez Gene: APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D (putative)". 

Further reading[edit]