AQP5

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AQP5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAQP5, AQP-5, PPKB, aquaporin 5
External IDsMGI: 106215 HomoloGene: 20398 GeneCards: AQP5
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for AQP5
Genomic location for AQP5
Band12q13.12Start49,961,872 bp[1]
End49,965,682 bp[1]
RNA expression pattern
PBB GE AQP5 213611 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001651

NM_009701

RefSeq (protein)

NP_001642

NP_033831

Location (UCSC)Chr 12: 49.96 – 49.97 MbChr 15: 99.59 – 99.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aquaporin-5 is a protein that in humans is encoded by the AQP5 gene.[5][6]

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions [6]. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000161798 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044217 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Lee MD, Bhakta KY, Raina S, Yonescu R, Griffin CA, Copeland NG, Gilbert DJ, Jenkins NA, Preston GM, Agre P (Jun 1996). "The human Aquaporin-5 gene. Molecular characterization and chromosomal localization". J Biol Chem. 271 (15): 8599–604. doi:10.1074/jbc.271.15.8599. PMID 8621489.
  6. ^ a b c "Entrez Gene: AQP5 aquaporin 5".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.