From Wikipedia, the free encyclopedia
Jump to: navigation, search
Aquaporin 5
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols AQP5 ; AQP-5; PPKB
External IDs OMIM600442 MGI106215 HomoloGene20398 IUPHAR: 692 GeneCards: AQP5 Gene
RNA expression pattern
PBB GE AQP5 213611 at tn.png
More reference expression data
Species Human Mouse
Entrez 362 11830
Ensembl ENSG00000161798 ENSMUSG00000044217
UniProt P55064 Q9WTY4
RefSeq (mRNA) NM_001651 NM_009701
RefSeq (protein) NP_001642 NP_033831
Location (UCSC) Chr 12:
49.96 – 49.97 Mb
Chr 15:
99.59 – 99.59 Mb
PubMed search [1] [2]

Aquaporin-5 is a protein that in humans is encoded by the AQP5 gene.[1][2]

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.[2]

See also[edit]


  1. ^ Lee MD, Bhakta KY, Raina S, Yonescu R, Griffin CA, Copeland NG, Gilbert DJ, Jenkins NA, Preston GM, Agre P (Jun 1996). "The human Aquaporin-5 gene. Molecular characterization and chromosomal localization". J Biol Chem 271 (15): 8599–604. doi:10.1074/jbc.271.15.8599. PMID 8621489. 
  2. ^ a b "Entrez Gene: AQP5 aquaporin 5". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.