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Aquaporin 7
Symbols AQP7 ; AQP7L; AQP9; AQPap; GLYCQTL
External IDs OMIM602974 MGI1314647 HomoloGene48000 IUPHAR: 694 GeneCards: AQP7 Gene
RNA expression pattern
PBB GE AQP7 206955 at tn.png
More reference expression data
Species Human Mouse
Entrez 364 11832
Ensembl ENSG00000165269 ENSMUSG00000028427
UniProt O14520 O54794
RefSeq (mRNA) NM_001170 NM_007473
RefSeq (protein) NP_001161 NP_031499
Location (UCSC) Chr 9:
33.38 – 33.4 Mb
Chr 4:
41.03 – 41.05 Mb
PubMed search [1] [2]

Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene.[1][2]

Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function.[2]

See also[edit]


  1. ^ Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S (Sep 1997). "Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea". J Biol Chem 272 (33): 20782–6. doi:10.1074/jbc.272.33.20782. PMID 9252401. 
  2. ^ a b "Entrez Gene: AQP7 aquaporin 7". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.