ARFIP2

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ARFIP2
Protein ARFIP2 PDB 1i49.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ARFIP2, POR1, ADP ribosylation factor interacting protein 2
External IDs MGI: 1924182 HomoloGene: 8234 GeneCards: ARFIP2
RNA expression pattern
PBB GE ARFIP2 202109 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001242854
NM_001242855
NM_001242856
NM_012402

NM_029802

RefSeq (protein)

NP_001229783
NP_001229784
NP_001229785
NP_036534

NP_084078.3
NP_084078

Location (UCSC) Chr 11: 6.47 – 6.48 Mb Chr 7: 105.63 – 105.64 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Arfaptin-2 is a protein that in humans is encoded by the ARFIP2 gene.[3][4][5]


Interactions[edit]

ARFIP2 has been shown to interact with Arf6,[6][7] ARF3,[4] ARF5[4][7] and RAC1.[3]{[7][8]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Van Aelst L, Joneson T, Bar-Sagi D (October 1996). "Identification of a novel Rac1-interacting protein involved in membrane ruffling". EMBO J. 15 (15): 3778–86. PMC 452058Freely accessible. PMID 8670882. 
  4. ^ a b c Kanoh H, Williger BT, Exton JH (April 1997). "Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes". J Biol Chem. 272 (9): 5421–9. doi:10.1074/jbc.272.9.5421. PMID 9038142. 
  5. ^ "Entrez Gene: ARFIP2 ADP-ribosylation factor interacting protein 2 (arfaptin 2)". 
  6. ^ D'Souza-Schorey, C; Boshans R L; McDonough M; Stahl P D; Van Aelst L (September 1997). "A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements". EMBO J. ENGLAND. 16 (17): 5445–54. doi:10.1093/emboj/16.17.5445. ISSN 0261-4189. PMC 1170175Freely accessible. PMID 9312003. 
  7. ^ a b c Shin, O H; Exton J H (August 2001). "Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1". Biochem. Biophys. Res. Commun. United States. 285 (5): 1267–73. doi:10.1006/bbrc.2001.5330. ISSN 0006-291X. PMID 11478794. 
  8. ^ Tarricone, C; Xiao B; Justin N; Walker P A; Rittinger K; Gamblin S J; Smerdon S J (May 2001). "The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways". Nature. England. 411 (6834): 215–9. doi:10.1038/35075620. ISSN 0028-0836. PMID 11346801. 

External links[edit]

Further reading[edit]