ARPC1A

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ARPC1A
Identifiers
Aliases ARPC1A, Arc40, HEL-68, SOP2Hs, SOP2L, HEL-S-307, actin related protein 2/3 complex subunit 1A
External IDs MGI: 1928896 HomoloGene: 4675 GeneCards: ARPC1A
RNA expression pattern
PBB GE ARPC1A 200950 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006409
NM_001190996

NM_019767

RefSeq (protein)

NP_001177925
NP_006400

NP_062741.1
NP_062741

Location (UCSC) Chr 7: 99.33 – 99.39 Mb Chr 5: 145.08 – 145.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Actin-related protein 2/3 complex subunit 1A is a protein that in humans is encoded by the ARPC1A gene.[3][4][5]

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.[5]

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