DDEF1

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  (Redirected from ASAP1 (gene))
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ASAP1
Protein DDEF1 PDB 2da0.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesASAP1, AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
External IDsMGI: 1342335 HomoloGene: 7684 GeneCards: ASAP1
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for ASAP1
Genomic location for ASAP1
Band8q24.21-q24.22Start130,052,104 bp[1]
End130,443,660 bp[1]
RNA expression pattern
PBB GE DDEF1 221039 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001247996
NM_018482
NM_001362925
NM_001362926
NM_001362924

NM_001276461
NM_001276462
NM_001276463
NM_001276467
NM_010026

RefSeq (protein)

NP_001234925
NP_060952
NP_001349854
NP_001349855
NP_001349853

NP_001263390
NP_001263391
NP_001263392
NP_001263396
NP_034156

Location (UCSC)Chr 8: 130.05 – 130.44 MbChr 15: 64.09 – 64.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 is a protein that in humans is encoded by the ASAP1 gene.[5][6]


Interactions[edit]

DDEF1 has been shown to interact with Src.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000153317 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022377 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Brown MT, Andrade J, Radhakrishna H, Donaldson JG, Cooper JA, Randazzo PA (Dec 1998). "ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src". Mol Cell Biol. 18 (12): 7038–51. PMC 109286. PMID 9819391.
  6. ^ "Entrez Gene: DDEF1 development and differentiation enhancing factor 1".
  7. ^ Brown, M T; Andrade J; Radhakrishna H; Donaldson J G; Cooper J A; Randazzo P A (Dec 1998). "ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src". Mol. Cell. Biol. UNITED STATES. 18 (12): 7038–51. ISSN 0270-7306. PMC 109286. PMID 9819391.

Further reading[edit]