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Protein ASCC3L1 PDB 2q0z.png
Available structures
PDBOrtholog search: PDBe RCSB
AliasesSNRNP200, ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, small nuclear ribonucleoprotein U5 subunit 200
External IDsMGI: 2444401 HomoloGene: 5859 GeneCards: SNRNP200
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for SNRNP200
Genomic location for SNRNP200
Band2q11.2Start96,274,336 bp[1]
End96,305,515 bp[1]
RNA expression pattern
PBB GE PNPLA6 203718 at tn.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 2: 96.27 – 96.31 MbChr 2: 127.21 – 127.24 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

U5 small nuclear ribonucleoprotein 200 kDa helicase is an enzyme that in humans is encoded by the SNRNP200 gene.[5][6][7][8][9]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000144028 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003660 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
  6. ^ Lauber J, Fabrizio P, Teigelkamp S, Lane WS, Hartmann E, Luhrmann R (Oct 1996). "The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases". EMBO J. 15 (15): 4001–15. PMC 452120. PMID 8670905.
  7. ^ Achsel T, Ahrens K, Brahms H, Teigelkamp S, Luhrmann R (Nov 1998). "The Human U5-220kD Protein (hPrp8) Forms a Stable RNA-Free Complex with Several U5-Specific Proteins, Including an RNA Unwindase, a Homologue of Ribosomal Elongation Factor EF-2, and a Novel WD-40 Protein". Mol Cell Biol. 18 (11): 6756–66. doi:10.1128/mcb.18.11.6756. PMC 109259. PMID 9774689.
  8. ^ Laggerbauer B, Achsel T, Luhrmann R (May 1998). "The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro". Proc Natl Acad Sci U S A. 95 (8): 4188–92. doi:10.1073/pnas.95.8.4188. PMC 22463. PMID 9539711.
  9. ^ "Entrez Gene: ASCC3L1 activating signal cointegrator 1 complex subunit 3-like 1".

External links[edit]

Further reading[edit]