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ATPase, class V, type 10A
External IDs OMIM605855 MGI1330809 HomoloGene56461 GeneCards: ATP10A Gene
EC number
RNA expression pattern
PBB GE ATP10A 214255 at tn.png
PBB GE ATP10A 214256 at tn.png
More reference expression data
Species Human Mouse
Entrez 57194 11982
Ensembl ENSG00000206190 ENSMUSG00000025324
UniProt O60312 O54827
RefSeq (mRNA) NM_024490 NM_009728
RefSeq (protein) NP_077816 NP_033858
Location (UCSC) Chr 15:
25.68 – 25.87 Mb
Chr 7:
58.66 – 58.83 Mb
PubMed search [1] [2]

Probable phospholipid-transporting ATPase VA also known as ATPase class V type 10A (ATP10A) or aminophospholipid translocase VA is an enzyme that in humans is encoded by the ATP10A gene.[1][2][3]


The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene is maternally expressed. It maps within the most common interval of deletion responsible for Angelman syndrome, also known as 'happy puppet syndrome'.[3]

See also[edit]


  1. ^ Halleck MS, Lawler JF JR, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Newman JT, Nakanishi Y, Ando H, Weinstock D, Williamson P, Schlegel RA (Oct 2000). "Differential expression of putative transbilayer amphipath transporters". Physiol Genomics 1 (3): 139–50. PMID 11015572. 
  2. ^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581. 
  3. ^ a b "Entrez Gene: ATP10A ATPase, Class V, type 10A". 

Further reading[edit]