ATXN2L

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ATXN2L
Identifiers
AliasesATXN2L, A2D, A2LG, A2LP, A2RP, ataxin 2 like
External IDsMGI: 2446242 HomoloGene: 16513 GeneCards: ATXN2L
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for ATXN2L
Genomic location for ATXN2L
Band16p11.2Start28,823,035 bp[1]
End28,837,237 bp[1]
RNA expression pattern
PBB GE ATXN2L 207798 s at fs.png

PBB GE ATXN2L 201806 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_183020
NM_001347658
NM_001361487

RefSeq (protein)

NP_001334587
NP_898841
NP_001348416

Location (UCSC)Chr 16: 28.82 – 28.84 MbChr 7: 126.49 – 126.5 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ataxin-2-like protein is a protein that in humans is encoded by the ATXN2L gene.[5][6][7]

This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.[7]

Interactions[edit]

ATXN2L has been shown to interact with Myeloproliferative leukemia virus oncogene.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168488 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032637 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ a b Meunier C, Bordereaux D, Porteu F, Gisselbrecht S, Chretien S, Courtois G (Mar 2002). "Cloning and characterization of a family of proteins associated with Mpl". J Biol Chem. 277 (11): 9139–47. doi:10.1074/jbc.M105970200. PMID 11784712. 
  6. ^ Figueroa KP, Pulst SM (Feb 2004). "Identification and expression of the gene for human ataxin-2-related protein on chromosome 16". Exp Neurol. 184 (2): 669–78. doi:10.1016/S0014-4886(03)00287-5. PMID 14769358. 
  7. ^ a b "Entrez Gene: ATXN2L ataxin 2-like". 

External links[edit]

Further reading[edit]