Acetarsol

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Acetarsol
Kekulé, skeletal formula of acetarsol
Names
Preferred IUPAC name
(3-Acetamido-4-hydroxyphenyl)arsonic acid
Other names
3-Acetamido-4-hydroxyphenylarsonic acid[citation needed]
Acetarsol
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.002.349
EC Number 202-582-3
KEGG
MeSH Acetarsol
UNII
UN number 3465
Properties
C8H10AsNO5
Molar mass 275.0903 g mol−1
Pharmacology
A07AX02 (WHO) G01AB01 (WHO), P01CD02 (WHO), P51AD05 (WHO)
Hazards
GHS pictograms The skull-and-crossbones pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The environment pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word Danger
H301, H331, H410
P261, P273, P301+310, P311, P501
Toxic T Dangerous for the Environment (Nature) N
R-phrases R23/25, R50/53
S-phrases S20/21, S28, S45, S60, S61
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Acetarsol is an anti-infective.[1]

It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol (fourneau is the French word for stove).[2][3]

It has been given in suppositories.[4]

Acetarsol can be used to make Arsthinol, & presumably Acetarsone also.

References[edit]

  1. ^ Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (April 1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS. 10 (4): 277–80. doi:10.1258/0956462991913943. PMID 12035784. 
  2. ^ Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
  3. ^ Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
  4. ^ Gionchetti P, Rizzello F, Morselli C, Campieri M (October 2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. doi:10.1111/j.1365-2036.2004.02049.x. PMID 15352902.