Acidic leucine-rich nuclear phosphoprotein 32 family member A

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Protein ANP32A PDB 2JE0.png
Available structures
PDB Human UniProt search: PDBe RCSB
Aliases ANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32, acidic nuclear phosphoprotein 32 family member A
External IDs HomoloGene: 133783 GeneCards: ANP32A
Gene location (Human)
Chromosome 15 (human)
Chr. Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for ANP32A
Genomic location for ANP32A
Band 15q23 Start 68,778,535 bp[1]
End 68,820,897 bp[1]
RNA expression pattern
PBB GE ANP32A 201043 s at fs.png

PBB GE ANP32A 201051 at fs.png

PBB GE ANP32A 201038 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 15: 68.78 – 68.82 Mb n/a
PubMed search [2] n/a
View/Edit Human

Acidic leucine-rich nuclear phosphoprotein 32 family member A is a protein that in humans is encoded by the ANP32A gene.[3][4][5] It is one of the targets of an oncomiR, MIRN21.


Acidic leucine-rich nuclear phosphoprotein 32 family member A has been shown to interact with MAP1B,[6] TAF1A[7] and Protein SET.[7][8]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140350 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". 
  3. ^ Chen TH, Brody JR, Romantsev FE, Yu JG, Kayler AE, Voneiff E, Kuhajda FP, Pasternack GR (March 1997). "Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci". Mol Biol Cell. 7 (12): 2045–56. doi:10.1091/mbc.7.12.2045. PMC 276049Freely accessible. PMID 8970164. 
  4. ^ Ulitzur N, Humbert M, Pfeffer SR (June 1997). "Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules". Proc Natl Acad Sci U S A. 94 (10): 5084–9. doi:10.1073/pnas.94.10.5084. PMC 24635Freely accessible. PMID 9144194. 
  5. ^ "Entrez Gene: ANP32A Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A". 
  6. ^ Opal, Puneet; Garcia Jesus J; Propst Friedrich; Matilla Antoni; Orr Harry T; Zoghbi Huda Y (September 2003). "Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis". J. Biol. Chem. United States. 278 (36): 34691–9. doi:10.1074/jbc.M302785200. ISSN 0021-9258. PMID 12807913. 
  7. ^ a b Seo, S B; McNamara P; Heo S; Turner A; Lane W S; Chakravarti D (January 2001). "Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein". Cell. United States. 104 (1): 119–30. doi:10.1016/S0092-8674(01)00196-9. ISSN 0092-8674. PMID 11163245. 
  8. ^ Fan, Zusen; Beresford Paul J; Zhang Dong; Lieberman Judy (April 2002). "HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Mol. Cell. Biol. United States. 22 (8): 2810–20. doi:10.1128/MCB.22.8.2810-2820.2002. ISSN 0270-7306. PMC 133744Freely accessible. PMID 11909973. 

Further reading[edit]

External links[edit]