Acolbifene

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Acolbifene
Acolbifene.svg
Clinical data
Synonyms EM-652; SCH-57068
Drug class Selective estrogen receptor modulator
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
Formula C29H31NO4
Molar mass 457.57 g·mol−1
3D model (JSmol)

Acolbifene (INN) (developmental code names EM-652, SCH-57068) is a nonsteroidal selective estrogen receptor modulator (SERM) which, as of 2015, is in phase III clinical trials for the treatment of breast cancer.[1][2]

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References[edit]

  1. ^ Gauthier, S; Cloutier, J; Dory, YL; Favre, A; Mailhot, J; Ouellet, C; Schwerdtfeger, A; Mérand, Y; Martel, C; Simard, J; Labrie, F (2005). "Synthesis and structure-activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution". Journal of enzyme inhibition and medicinal chemistry. 20 (2): 165–77. doi:10.1080/14756360500043448. PMID 15968821. 
  2. ^ http://adisinsight.springer.com/drugs/800013630

External links[edit]