Aconitic acid

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Aconitic acid[1]
Cis-aconitic acid.png
cis-aconitic acid
Trans-aconitic acid.png
trans-aconitic acid
IUPAC name
Prop-1-ene-1,2,3-tricarboxylic acid
Other names
Achilleic acid; Equisetic acid; Citridinic acid; Pyrocitric acid
3D model (Jmol)
ECHA InfoCard 100.007.162
MeSH Aconitate
Molar mass 174.11 g·mol−1
Appearance Colorless crystals
Melting point 190 °C (374 °F; 463 K) (decomposes) (trans isomer), 122 °C (cis isomer)
Acidity (pKa) 2.80, 4.46 (trans isomer)[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Aconitic acid is an organic acid. The two isomers are cis-aconitic acid and trans-aconitic acid. The conjugate base of cis-aconitic acid, cis-aconitate is an intermediate in the isomerization of citrate to isocitrate in the citric acid cycle. It is acted upon by the enzyme aconitase.

Aconitic acid can be synthesized by dehydration of citric acid using sulfuric acid:[3]


It was first prepared by thermal dehydration.[4]


  1. ^ "Aconitic Acid - Compound Summary (CID 309)". PubChem. 
  2. ^ Dawson, R. M. C.; Elliott, D. C.; Elliott, W. H. (1989). Data for Biochemical Research (3rd ed.). Oxford: Clarendon Press. ISBN 9780198552994. 
  3. ^ Bruce, W. F. (1937). "Aconitic Acid". Org. Synth. 17: 1. ; Coll. Vol., 2, p. 12 
  4. ^ Pawolleck, B. (1875). "Substitutionsproducte der Citronensäure und ein Versuch zur Synthese der letzteren" [Substitution products of citric acid and an attempt at the synthesis of the latter]. Justus Liebig's Annalen der Chemie. 178 (2–3): 150–170. doi:10.1002/jlac.18751780203.