Acquired hemolytic anemia

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Acquired hemolytic anemia
Classification and external resources
Specialty hematology
ICD-10 D59
ICD-9-CM 283

Acquired hemolytic anemia can be divided into immune and non-immune mediated forms of hemolytic anemia.


Immune mediated hemolytic anaemia (direct Coombs test is positive)


Non-immune mediated hemolytic anemia (direct Coombs test is negative)

Drug induced hemolysis[edit]

Drug induced hemolysis has large clinical relevance. It occurs when drugs actively provoke red blood cell destruction. It can be divided in the following manner:

A total of four mechanisms are usually described, but there is some evidence that these mechanisms may overlap.[1]


  1. ^ Wright MS (1999). "Drug-induced hemolytic anemias: increasing complications to therapeutic interventions". Clin Lab Sci. 12 (2): 115–8. PMID 10387489.