Acyl-lysine deacylase

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acyl-lysine deacylase
Identifiers
EC number3.5.1.17
CAS number9025-11-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an acyl-lysine deacylase (EC 3.5.1.17) is an enzyme that catalyzes the chemical reaction

N6-acyl-L-lysine + H2O a carboxylate + L-lysine

Thus, the two substrates of this enzyme are N6-acyl-L-lysine and H2O, whereas its two products are carboxylate and L-lysine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N6-acyl-L-lysine amidohydrolase. Other names in common use include epsilon-lysine acylase, and 6-N-acyl-L-lysine amidohydrolase. This enzyme participates in lysine degradation.

References[edit]

  • PAIK WK, BLOCH-FRANKENTHAL L, BIRNBAUM SM, WINITZ M, GREENSTEIN JP (1957). "epsilon-lysine acylase". Arch. Biochem. Biophys. 69: 56–66. doi:10.1016/0003-9861(57)90472-1. PMID 13445179.