Acylglycerol kinase

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acylglycerol kinase
EC no.
CAS no.62213-37-0
IntEnzIntEnz view
ExPASyNiceZyme view
MetaCycmetabolic pathway
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an acylglycerol kinase (EC is an enzyme that catalyzes the chemical reaction

ATP + acylglycerol ADP + acyl-sn-glycerol 3-phosphate

The two substrates of this enzyme are ATP and acylglycerol, whereas its two products are ADP and acyl-sn-glycerol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:acylglycerol 3-phosphotransferase. Other names in common use include monoacylglycerol kinase, monoacylglycerol kinase (phosphorylating), sn-2-monoacylglycerol kinase, MGK, monoglyceride kinase, and monoglyceride phosphokinase. This enzyme participates in glycerolipid metabolism.


  • Pieringer RA, Hokin LE (March 1962). "Biosynthesis of lysophosphatdic acid from monoglyceride and adenosine triphosphate". The Journal of Biological Chemistry. 237: 653–8. PMID 14486486.
  • Pieringer RA, Kunnes RS (July 1965). "The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in Escherichia coli" (PDF). The Journal of Biological Chemistry. 240 (7): 2833–8. PMID 14342303.