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Monoclonal antibody
Type Whole antibody
Source Human
Target EpCAM
CAS Number 503605-66-1 N
ATC code none
ChemSpider none
Chemical data
Formula C6552H10080N1740O2052S46
Molar mass 147.5 kg/mol
 NYesY (what is this?)  (verify)

Adecatumumab (MT201) is a recombinant human monoclonal antibody which is used to target tumor cells. It binds to the epithelial cell adhesion molecule (EpCAM - CD326).

Adecatumumab has been used in clinical studies of treatment in prostate[1] and breast cancers.[2]


  1. ^ Oberneder R, Weckermann D, Ebner B, et al. (October 2006). "A phase I study with adecatumumab, a human antibody directed against epithelial cell adhesion molecule, in hormone refractory prostate cancer patients". Eur. J. Cancer. 42 (15): 2530–8. doi:10.1016/j.ejca.2006.05.029. PMID 16930989. 
  2. ^ Prang N, Preithner S, Brischwein K, et al. (January 2005). "Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines". Br. J. Cancer. 92 (2): 342–9. doi:10.1038/sj.bjc.6602310. PMC 2361858free to read. PMID 15655555.