In 1981 she formed her own designer House Adeline André. That same year she also registered her most famous fashion innovation, the "three sleeve holes" at the French National Industrial Property Institute and 1982 at the World Intellectual Property Organization. Examples of this three sleeve holes garment are in the collections of French Fashion Museum, Palais Galliera in Paris, the Fashion Institute of Technology in New York and the Fashion and Design Museum in Lisbon.
In May 1997, Adeline André became an 'invited member‘ of the Syndicate Chamber of Parisian Haute Couture and a 'permanent member‘ since January 2005. She is currently the head designer at the fashion house that bears her name. Adeline André also teaches color at her alma mater, participates in gallery and museum exhibitions, and designs costumes for ballet, opera and theater.