Adhyperforin

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Adhyperforin
Adhyperforin2DACS.svg
Adhyperforin3Dan2.gif
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
Formula C36H54O4
Molar mass 550.81156 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

Adhyperforin is a phytochemical found in the members of the plant genus Hypericum including St. John's Wort.[1] It has a very similar pharmacological profile to hyperforin and acts as a TRPC6 ion channel activator,[1] thereby inhibiting the reuptake of various neurotransmitters including serotonin, norepinephrine, dopamine, GABA, and glutamate.[1] Adhyperforin is found in St. John's Wort in levels approximately 1/10 those of hyperforin.[1]

See also[edit]

References[edit]

  1. ^ a b c d Jensen AG, Hansen SH, Nielsen EO (2001). "Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity". Life Sci. 68 (14): 1593–1605. doi:10.1016/S0024-3205(01)00946-8. PMID 11263672.