Adrian R. Krainer

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Adrian R. Krainer is a Uruguayan-American Biochemist and Molecular Geneticist. Krainer holds the St. Giles Foundation Professorship at Cold Spring Harbor Laboratory. He is a 2019 Breakthrough Prize in Life Sciences for his contributions to the understanding of the RNA gene-splicing process and, in collaboration with fellow Prize Laureate Dr. Frank Bennet of Ionis Pharmaceuticals, the development of medical interventions that target the gene-splicing process, including Spinraza, which is the first treatment for the genetic disorder Spinal Muscular Atrophy.

Early life and education[edit]

Adrian R. Krainer was born in Montevideo, Uruguay to a Jewish family of Hungarian and Romanian descent. He has one older brother, who is a chemical engineer. His father did forced labor for two years in a Romanian labor camp (Ferma Alba) during World War II. After the war, his father's original surname, Kreiner changed to Krainer due to a clerical error when he was a refugee in Italy. His parents owned a small leather business in Montevideo. Krainer attended a private bilingual French-Spanish elementary school. He later attended a public school for two years before completing his pre-college education with four years at a private Spanish-Hebrew school. Krainer lived through political unrest during his teenage years, including urban guerrilla and military dictatorship. Krainer received a full scholarship from Columbia University and completed a Bachelor of Arts in Biochemistry in 1981. He graduated cum laude and Phi Beta Kappa. In 1986, he earned a Doctor of Philosophy in Biochemistry from Harvard University.[1]


From 1986-1989, Krainer conducted postdoctoral research as the first Cold Spring Harbor Fellow at the Cold Spring Harbor Laboratory. Krainer worked as an Assistant Professor from 1989-1990, Associate Professor from 1990-1994, and Professor since 1994. Krainer is a faculty member of the graduate programs in Genetics, Molecular and Cellular Biology, and Molecular Genetics and Microbiology at State University of New York, Stony Brook.[1] Krainer holds the St. Giles Foundation Professorship at Cold Spring Harbor Laboratory.[2]


  1. ^ a b Maestrejuan, Andrea R. (September 9, 1997). "ADRIAN R. KRAINER" (PDF). Chemical Heritage Foundation. Retrieved October 16, 2018.
  2. ^ "Adrian R. Krainer - Cold Spring Harbor Laboratory". Cold Spring Harbor Laboratory. Retrieved October 16, 2018.