Affective spectrum

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Not to be confused with Bipolar spectrum.

The affective spectrum is a spectrum of affective disorders (Mood disorders). It is a grouping of related psychiatric and medical disorders which may accompany bipolar, unipolar, and schizoaffective disorders at statistically higher rates than would normally be expected. These disorders are identified by a common positive response to the same types of pharmacologic treatments. They also aggregate strongly in families and may therefore share common heritable underlying physiologic anomalies.

Affective spectrum disorders include:

The following may also be part of the spectrum accompanying affective disorders[citation needed].

Also, there are now studies linking heart disease[citation needed].

Many of the terms above overlap. The American Psychiatric Association's definitions of these terms can be found in the Diagnostic and Statistical Manual of Mental Disorders (DSM).


  1. ^ a b c d e f g h Hudson JI, Pope HG Jr. (1990). "Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology?". Am J Psychiatry 147 (5): 552–64. PMID 11859906. 
  2. ^ a b c d e f g h i j k l m Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT (1990). "Family study of affective spectrum disorder". Arch Gen Psychiatry 60 (2): 170–7. doi:10.1001/archpsyc.60.2.170. PMID 12578434. 

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