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Aglaia roxburghiana 03.JPG
Aglaia roxburghiana
Scientific classification e
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Sapindales
Family: Meliaceae
Subfamily: Melioideae
Genus: Aglaia

Over 390, see text.

Aglaia is a genus of 117 species[1] of woody trees belonging to the Mahogany family (Meliaceae). These trees occur in the subtropical and tropical forests of Southeast Asia, Northern Australia and the Pacific.

Some species are important timber trees; others have scented flowers, or medicinal properties (the edible fruits duku or langsat have now been placed in the genus Lansium). Many have complex biological relationships with their dispersal agents.


Species in the genus Aglaia synthesize a unique class of highly bioactive chemical compounds known as flavaglines. Over 50 unique compounds of this class have been described so far, including rocaglamide, aglafoline, silvestrol, pannellin, episilvestrol, and ponapensin.[2][3][4][5][6] They are known for their anti-cancer, anti-fungal, anti-inflammatory and insecticidal properties. Several of these compounds have been shown to be exceptional therapeutic agents for cancer chemotherapy, however further research is needed to develop medicines.[2]


Due to considerable morphological variation, this genus presents numerous taxonomic problems, with the number of accepted species varying from 117[1] to over 390 depending on the species concept used.[7][8]


  1. ^ a b "Aglaia Lour. | Plants of the World Online | Kew Science". Plants of the World Online. Retrieved 2020-02-07.
  2. ^ a b Kim, Soyoung; Salim, Angela; Swanson, Steven; Douglas Kinghorn, A. (2006-07-01). "Potential of Cyclopenta[b]benzofurans from Aglaia Species in Cancer Chemotherapy". Anti-Cancer Agents in Medicinal Chemistry. 6 (4): 319–345. doi:10.2174/187152006777698123. ISSN 1871-5206. PMID 16842234.
  3. ^ Ribeiro, Nigel; Thuaud, Frédéric; Nebigil, Canan; Désaubry, Laurent (March 2012). "Recent advances in the biology and chemistry of the flavaglines". Bioorganic & Medicinal Chemistry. 20 (6): 1857–1864. doi:10.1016/j.bmc.2011.10.048. ISSN 0968-0896. PMID 22071525.
  4. ^ Hwang, Bang Yeon; Su, Bao-Ning; Chai, Heebyung; Mi, Qiuwen; Kardono, Leonardus B. S.; Afriastini, Johar J.; Riswan, Soedarsono; Santarsiero, Bernard D.; Mesecar, Andrew D.; Wild, Robert; Fairchild, Craig R. (May 2004). "Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives fromAglaia silvestris". The Journal of Organic Chemistry. 69 (10): 3350–3358. doi:10.1021/jo040120f. ISSN 0022-3263. PMID 15132542.
  5. ^ Brader, G.; Vajrodaya, S.; Greger, H.; Bacher, M.; Kalchhauser, H.; Hofer, O. (December 1998). "Bisamides, Lignans, Triterpenes, and Insecticidal Cyclopenta[b]benzofurans fromAglaiaSpecies1". Journal of Natural Products. 61 (12): 1482–1490. doi:10.1021/np9801965. ISSN 0163-3864. PMID 9868148.
  6. ^ Salim, Angela A.; Pawlus, Alison D.; Chai, Hee-Byung; Farnsworth, Norman R.; Douglas Kinghorn, A.; Carcache-Blanco, Esperanza J. (January 2007). "Ponapensin, a cyclopenta[bc]benzopyran with potent NF-κB inhibitory activity from Aglaia ponapensis". Bioorganic & Medicinal Chemistry Letters. 17 (1): 109–112. doi:10.1016/j.bmcl.2006.09.084. ISSN 0960-894X. PMC 2786496. PMID 17055270.
  7. ^ Muellner, Alexandra N.; Samuel, Rosabelle; Chase, Mark W.; Pannell, Caroline M.; Greger, Harald (2005). "Aglaia (Meliaceae): an evaluation of taxonomic concepts based on DNA data and secondary metabolites". American Journal of Botany. 92 (3): 534–543. doi:10.3732/ajb.92.3.534. PMID 21652432.
  8. ^ Grudinski, Melanie; Pannell, Caroline M.; Chase, Mark W.; Ahmad, Joffre A.; Muellner-Riehl, Alexandra N. (April 2014). "An evaluation of taxonomic concepts of the widespread plant genus Aglaia and its allies across Wallace's Line (tribe Aglaieae, Meliaceae)". Molecular Phylogenetics and Evolution. 73: 65–76. doi:10.1016/j.ympev.2014.01.025. ISSN 1055-7903. PMID 24495856.

External links[edit]

  • Pannell, C.M. (1992). A taxonomic monograph of the genus Aglaia Lour. (Meliaceae). Kew Bulletin Additional Series. XV1. London: HMSO. ISBN 978-0-11-250067-4.
  • Pannell, C.M. (1997). Dranseld, J.; et al. (eds.). Solving problems in the taxonomy of Aglaia (Meliaceae): functional syndromes and the biological monograph. Pl. Div. Mal. III. pp. 163–170.
  • Satasook, C.; Isman, M.B.; Ishibashi, F.; Medbury, S.; Wiriyachitra, P.; Towers, G.H.N. (1994), "Insecticidal bioactivity of crude extracts of Aglaia species (Meliaceae)", Biochemical Systematics and Ecology, 22 (2): 121–7, doi:10.1016/0305-1978(94)90002-7
  • "Aglaia Lour". Atlas of Living Australia.

Data related to Aglaia at Wikispecies

Media related to Aglaia at Wikimedia Commons