After appearing in a few commercials Jaffri appeared in her first serial, Zip Bus Chup Raho, where she played a supporting character. Her next serial Dreamers was a youth oriented show. She then appeared in a supporting role in the serial Badtameez. She also appeared in a string of telefilms in the Kitni Girhain Baqi Hain series and appeared in the second season of the sitcom Kya Life Hai.
In 2013 she made her Lollywood debut in Humyun Saeed's production Main Hoon Shahid Afridi.[2] Ainy Jaffri has also rendered the voice of the main character in Pakistan's first super hero cartoon, "Burka Avenger".
On 28 September 2013, Jaffri became engaged to Faris Rahman who works as an equity analyst at Fidelity Investments in London.[3] and the couple were married on 22 February 2014.