Akio Sasajima (笹島 明夫? Sasajima Akio) (born 1952) is a jazz guitarist born in Japan and currently based in Nevada City, California. His playing style incorporates bebop, hard bop, and jazz fusion. He recorded several albums as a leader for Muse and Enja in the late 1980s and early 1990s.
- Akio with Joe Henderson (Muse, 1988)
- Time Remembered (Muse, 1989)
- Akioustically Sound (Muse, 1991)
- Humpty Dumpty (Enja, 1993)
- Two for the Muse (Pony Canyon, 2006)