Akkermansia is a genus in the phylum Verrucomicrobia (Bacteria). The genus was first proposed in 2004 by Muriel Derrien and others, with the type species Akkermansia muciniphila (gen. nov., sp. nov).
The name Akkermansia derives from:
New Latin feminine gender noun Akkermansia, named after Antoon DL Akkermans (28 October 1940 – 21 August 2006), a Dutch microbiologist recognized for his contribution to microbial ecology.
The genus contains a single species, namely A. muciniphila ( Derrien et al. 2004, (Type species of the genus).; New Latin neuter gender noun mucinum, mucin; New Latin adjective philus from Greek adjective philos (φίλος) meaning friend, loving; New Latin feminine gender adjective muciniphila, mucin-loving.)
Description of Akkermansia gen. nov.
Akkermansia (Ak.ker.man'si.a. N.L. fem. n. Akkermansia derived from Antoon Akkermans, a Dutch microbiologist recognized for his contribution to microbial ecology). Cells are oval-shaped, non-motile and stain Gram-negative. Strictly anaerobic. Chemo-organotrophic. Mucolytic in pure culture.:1474
||This section needs more medical references for verification or relies too heavily on primary sources. (September 2015)|
Akkermansia muciniphila, the only currently known species within genus Akkermansia, can reside in the human intestinal tract and is currently being studied for its effects on human metabolism. Recently performed studies in rodents have indicated that Akkermansia muciniphila in the intestinal tract may mediate obesity, diabetes, and inflammation.
- Classification of Genera AC entry in LPSN [Euzéby, J.P. (1997). "List of Bacterial Names with Standing in Nomenclature: a folder available on the Internet". Int J Syst Bacteriol. 47 (2): 590–2. doi:10.1099/00207713-47-2-590. ISSN 0020-7713. PMID 9103655.]
- Derrien, M. (2004). "Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium". International Journal of Systematic and Evolutionary Microbiology. 54 (5): 1474. doi:10.1099/ijs.0.02873-0. ISSN 1466-5026.
- In memory of Antonius Dirk Louis (Anton) Akkermans, Springer Reference, retrieved 30 April 2014
- Akkermansia entry in LPSN [Euzéby, J.P. (1997). "List of Bacterial Names with Standing in Nomenclature: a folder available on the Internet". Int J Syst Bacteriol. 47 (2): 590–2. doi:10.1099/00207713-47-2-590. ISSN 0020-7713. PMID 9103655.]
- Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium
- Everard, A.; Belzer, C.; Geurts, L.; Ouwerkerk, J. P.; Druart, C.; Bindels, L. B.; Guiot, Y.; Derrien, M.; Muccioli, G. G.; Delzenne, N. M.; de Vos, W. M.; Cani, P. D. (2013). "Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity". Proceedings of the National Academy of Sciences. 110 (22): 9066–9071. doi:10.1073/pnas.1219451110. ISSN 0027-8424.
- Wageningen University and Research Centre (2013, May 15). Intestinal bacterium Akkermansia curbs obesity. ScienceDaily. Retrieved August
- REILLY, RACHEL (13 May 2013). "Good gut bacteria could provide new treatment for obesity and diabetes". Daily Mail. Retrieved 25 August 2013.
- Caesar, Robert; Tremaroli, Valentina; Kovatcheva-Datchary, Petia; Cani, Patrice D.; Bäckhed, Fredrik (2015). "Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling". Cell Metabolism. 22: 658–668. doi:10.1016/j.cmet.2015.07.026. Retrieved 2015-08-31.
Mice that received microbiota from a lard-fed donor showed increased adiposity and inflammation, together with a significant increase in Lactobacillus, compared to mice that received microbiota from a fish-oil-fed donor. Therefore, these data do not provide evidence for a role of Lactobacillus in reducing inflammation. However, we found that the enrichment of Akkermansia co-occurred with partial protection against adiposity and inflammation in mice transplanted with fish-oil microbiota and fed a lard diet, highlighting Akkermansia as a potential mediator of the improved inflammatory and metabolic phenotype of mice fed fish oil.
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