Skene was born in Fyvie, Scotland, United Kingdom on 17 June 1837. At the age of 19, he went to America. He studied medicine at King's College (now the University of Toronto), then at the University of Michigan, and finally at the Long Island College Hospital (now the State University of New York Downstate Medical Center) in Brooklyn graduating in 1863. From July 1863 until June 1864, he was acting assistant surgeon in the U. S. Army, after which he entered private practice in Brooklyn and advanced to become Professor of Disease of Women at Long Island College Hospital. He was professor of gynaecology in the post-graduate Medical School of New York in 1884, and was president of the American Gynaecological Society.
Skene wrote over 100 medical articles and several textbooks. He contributed many surgical instruments and improved on surgical techniques. He performed the first successful operation of gastro-elytrotomy that is recorded, and also that of craniotomy, using Sims's speculum. Primarily, he is remembered for his description of the Skene's glands at the floor of the urethra. He also described their infection - skenitis.
As a sculptor, Skene created a bust of J. Marion Sims, which is on display in the lobby of the Kings County Medical Society. A bust honoring him is located in Prospect Park Plaza (also known as Grand Army Plaza). This statue was moved in 2011 to accommodate a statue of Abraham Lincoln, a former U.S. president.
Skene died in his summerhouse in the Catskills, New York on July 4, 1900. He left behind a son, Jonathan Bowers.
- Uro-Cystic and Urethral Diseases in Women (New York, 1877)
- Treatise on Diseases of Women, for the Use of Students and Practitioners (1888)
||This article includes a list of references, related reading or external links, but its sources remain unclear because it lacks inline citations. (December 2014)|
- Chesley LC: The evolution of the department of obstetrics and gynecology at Downstate 1860-1980. 1981.
- Wilson, James Grant; Fiske, John, eds. (1900). "Skene, Alexander Johnston Chalmers". Appletons' Cyclopædia of American Biography. New York: D. Appleton.