Cobrin was born and raised in Chicago, Illinois. She attended high school at the Chicago Academy for the Arts where she majored in musical theater. Growing up, she trained to become a classical ballerina and competed in the Junior Olympics. Ali has one brother, and two half sisters.
Cobrin began her entertainment career as an improvisation player in Second City's teen ensemble and danced with the Burklyn Ballet Theater touring Scotland, where she performed at the Edinburgh Fringe Festival. During that same time, Cobrin had workshopped Broadway musicals, including All That Jazz and Wonderland, which were directed by Ben Vereen and Frank Wildhorn, respectively. After graduating high school at the age of 17, Cobrin moved to Los Angeles, California to pursue an acting career.
Upon moving to Los Angeles, Cobrin had her first film acting role in a 2008 short film entitled One. That same year, she starred in another short film called Jack Turner and the Reluctant Vampire, which won two awards in the Los Angeles Accolade Competition. In 2009, Cobrin had a supporting role in The Hole, a 3D film directed by Joe Dante. The film would win the first Premio Persol award for best 3-D movie at the 2009 Venice Film Festival. In 2010, Cobrin made her debut television appearance in Kings by Night, a comedy pilot for Spike TV, and Showtime's LOOK. Later that year, she had a lead actress role in the film Cold Cabin, and appeared opposite to rapper B.o.B in the Adidas Originals shoe campaign commercial, MEGA Diner. In 2011, she guest starred in the television series, Friends with Benefits. In 2012, Cobrin had a supporting role in American Reunion, a sequel in the American Pie film series. The same year, she starred in Life’s an Itch. In 2015, she portrayed Kylie Atkins in Trevor Matthews' horror thriller film Girl House, in which she co-starred with Slaine. She portrayed also Joan in the Drama thriller film Outlaw, which was directed by Todd Shields and Julia in Michaël Nakache Drama film Connected.
|2008||Jack Turner and the Reluctant Vampire||Val||Short film|
|2012||Life's an Itch||Gillian Gracin|
|2014||Girl House||Kylie Atkins|
|2014||A Beautiful Now||Tracey|
|2010||Look: The Series||Molly||Main role; 11 episodes|
|2010||Kings by Night||Amber||Unaired Spike pilot|
|2011||Friends with Benefits||Hope Prater||Episode: "The Benefit of Being Shallow"|
|2015||The Unauthorized Melrose Place Story||Daphne Zuniga||Television film|
|2018||The Baxters||Kari Baxter||Television Series|
|2018||Deadly Matrimony||Parker Wyndham||Television film|
- Hurwitz, Jon. "Happy Birthday @AliCobrin! She's the lovely Kara from American Reunion for those not in the know. Follow her!". Retrieved 1 December 2017.
- "Ali Cobrin". Maxim. Retrieved 13 April 2015.
- Cobrin, Ali. "Bio". Ali Cobrin. Archived from the original on 2012-04-10. Retrieved 8 April 2012.
- "The Hottie Stop Interviews Ali Cobrin, star of GirlHouse!". JoBlo.com. 2015-02-16. Retrieved 2015-04-13.
- Cudworth, Tom. "Dancing For Krumholtz". The Common Tongue. Archived from the original on 2013-04-16. Retrieved 8 April 2012.
- Rifkin, Adam. "LOOK THE SERIES". SHOWTIME. Retrieved 8 April 2012.
- Elley, Derek (11 September 2009). "Review: 'The Hole'". Variety. Retrieved 13 April 2015.
- Hayes, Britt (14 September 2009). "Joe Dante's The Hole Wins Venice Prize". Brutal as Hell. Archived from the original on 24 September 2009. Retrieved 13 April 2015.
- Barone, Matt (6 April 2012). "Interview: "American Reunion" Directors Talk Bringing The "American Pie" Kids Into Their 30s". Complex.com. Retrieved 13 April 2015.
- McIlhone, Sally (16 May 2012). "Miss American Pie: introducing Ali Cobrin". FHM.
- Miska, Brad. "Ali Cobrin Girl House". Bloody Disgusting. Retrieved 8 April 2012.
- Hallam, Scott. "Exclusive: Ali Cobrin and Slaine Talk About Living in the Girl House". Dread Central. Retrieved 8 April 2012.