Alizapride

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Alizapride
Alizapride.svg
3D Alizapride.png
Systematic (IUPAC) name
N-[(1-Allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral, IM, IV
Legal status
Legal status
  • ℞ (Prescription only)
Pharmacokinetic data
Biological half-life 3 hours
Excretion Renal
Identifiers
CAS Number 59338-93-1 YesY
ATC code A03FA05 (WHO)
PubChem CID 43008
DrugBank DB01425 YesY
ChemSpider 39202 YesY
UNII P55703ZRZY YesY
KEGG D07102 YesY
ChEMBL CHEMBL290194 YesY
Chemical data
Formula C16H21N5O2
Molar mass 315.37 g/mol
  (verify)

Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.[1]

References[edit]

  1. ^ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol 22 (4): 316–20. doi:10.1007/bf00254238. PMID 3048762.