Alkylacetylglycerophosphatase

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alkylacetylglycerophosphatase
Identifiers
EC number 3.1.3.59
CAS number 102925-45-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an alkylacetylglycerophosphatase (EC 3.1.3.59) is an enzyme that catalyzes the chemical reaction

1-alkyl-2-acetyl-sn-glycero-3-phosphate + H2O 1-alkyl-2-acetyl-sn-glycerol + phosphate

Thus, the two substrates of this enzyme are 1-alkyl-2-acetyl-sn-glycero-3-phosphate and H2O, whereas its two products are 1-alkyl-2-acetyl-sn-glycerol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase. Other names in common use include 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase, and alkylacetylglycerophosphate phosphatase. This enzyme participates in ether lipid metabolism.

References[edit]

  • Lee TC, Malone B, Snyder F (1986). "A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen". J. Biol. Chem. 261 (12): 5373–7. PMID 3007498.