Allen Frances

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Allen J. Frances
Born1942 (age 78–79)
NationalityAmerican
Alma materColumbia College (1963)
SUNY Downstate College of Medicine (1967)
Occupationpsychiatrist

Allen J. Frances (born 1942) is an American psychiatrist. He is currently Professor and Chairman Emeritus of the Department of Psychiatry and Behavioral Sciences at Duke University School of Medicine. He is best known for serving as chair of the American Psychiatric Association task force overseeing the development and revision of the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). Frances is the founding editor of two well-known psychiatric journals: the Journal of Personality Disorders and the Journal of Psychiatric Practice.

During the development of the current diagnostic manual, DSM-5, Frances became critical of the expanding boundaries of psychiatry and the medicalization of normal human behavior, problems he contends are leading to the overdiagnosis and overtreatment of the "worried well" and the gross undertreatment of the severely ill. In recent years, Frances has become a vocal advocate for improved treatment and societal conditions for the seriously mentally ill, the appropriate use of electroconvulsive therapy in severe cases of mental disorder, and an integrated, biopsychosocial approach to psychiatry.

Frances is the author or co-author of multiple books within the fields of psychiatry and psychology, including: Differential Therapeutics (1984),[1] Your Mental Health (1999),[2] Saving Normal (2013),[3] Essentials of Psychiatric Diagnosis (2013),[4] and Twilight of American Sanity (2017).[5][6][7]

Education and career[edit]

Education[edit]

Frances was born and raised in New York City, US.[8] He received his bachelor's degree from Columbia College in 1963 and his medical degree in 1967 from SUNY Downstate College of Medicine.[9][10][11] He graduated from the psychiatry residency training program at the New York State Psychiatric Institute in 1971 and received a certificate in psychoanalytic medicine from Columbia University Center for Psychoanalytic Training and Research in 1978.[12] His research in the fields of psychiatry and behavioral sciences focused on schizophrenia, personality disorders, anxiety disorders, mood disorders, and clinical treatment of psychiatric patients.[10]

Career[edit]

Frances' early career was spent at Cornell University Medical College, where he rose to the rank of professor, headed the outpatient department, saw patients, taught, established a brief therapy program, and developed research specialty clinics for schizophrenia, depression, anxiety disorders, and AIDS. Throughout his academic career, Frances was an active investigator and prolific author in a surprisingly wide range of clinical areas including personality disorders, chronic depression, anxiety disorders, schizophrenia, AIDS, and psychotherapy. In 1991, he became chairman of the Department of Psychiatry at Duke University School of Medicine, where he helped to expand the research, training, and clinical programs that had been initiated by his predecessor as chair, Dr. Bernard Carroll.[10][13][14]

Publications[edit]

Frances' book on Differential Therapeutics (1984) tried to bring specificity and evidence to decisions on how best to match patient and treatment.[1] His recognition of therapeutic limits resulted in the 1981 paper No Treatment as the Prescription of Choice.[15] Frances was the founding editor of two journals that have become standards: The Journal of Personality Disorders and the Journal of Psychiatric Practice.[14]

In 2013, Allen Frances wrote a paper entitled "The New Crisis of Confidence in Psychiatric Diagnosis", which said that "psychiatric diagnosis still relies exclusively on fallible subjective judgments rather than objective biological tests".[16][17] Frances was also concerned about "unpredictable overdiagnosis".[16]

The Diagnostic and Statistical Manual of Mental Disorders[edit]

DSM-IV[edit]

Despite its conservative intent and careful methodology, DSM-IV was not able to prevent diagnostic inflation. Rates of attention deficit disorder tripled as a result of heavy drug company marketing starting in 1997—instigated by the introduction of new on-patent drugs and facilitated by the removal of federal prohibitions against direct-to-consumer advertising. Rates of autism increased by more than twentyfold largely because the loose diagnosis followed its becoming a prerequisite for extra school services. Rates of bipolar disorder doubled largely because of drug company marketing. And rates of bipolar disorder in children increased by fortyfold when thought leaders and drug companies convinced practitioners that temperamental kids had bipolar disorder even if they didn't have mood swings—a concept that had been rejected by DSM-IV. Frances later felt that DSM-IV should have fought more vigorously against the risks of diagnostic inflation by tightening diagnostic criteria and providing more specific warnings against over-diagnosis. Frances co-authored Your Mental Health: A Layman's Guide to the Psychiatrist's Bible (1999) with psychiatrist Michael First.[2]

DSM-5[edit]

The next revision DSM-5 was initiated with a 2002 book (A Research Agenda for DSM-V[18]) questioning the utility of the atheoretical, descriptive paradigm and suggesting a neuroscience research agenda aiming to develop a pathophysiologically based classification. After a series of symposiums, the task force began to work on the manual itself. In June 2008, Dr. Robert Spitzer who chaired the DSM-III and DSM-IIIR revisions had begun to write about the secrecy of the DSM-V Task Force (DSM-V: Open and Transparent?[19]). Frances initially declined to join Spitzer's criticism, but after learning about the changes being considered,[20] he wrote an article in July 2009 (A Warning Sign on the Road to DSM-V: Beware of Its Unintended Consequences[21]) expressing multiple concerns including the unsupported paradigm shift, a failure to specify the level of empirical support needed for changes, their lack of openness, their ignoring the negative consequences of their proposals, a failure to meet timelines, and anticipate the coming time pressures. The APA/DSM-V Task Force response dismissed his complaints.[22]

In March 2010, Frances began a weekly blog in Psychology Today, DSM-5 in Distress: The DSM's impact on mental health practice and research,[23] often cross-posted in the Psychiatric Times[24] and the Huffington Post.[25] While many of his blog posts were about the DSM-5 Task Force lowering the thresholds for diagnosing existing disorders (attention deficit disorder, autism, addictions, personality disorders, bipolar II disorder), he was also disturbed by the addition of new speculative disorders (Attenuated Psychosis Syndrome, Disruptive Mood Dysregulation Disorder, Somatic Symptom Disorder). He has argued that the diagnosis attenuated psychosis syndrome promoted by advocates of early intervention for psychosis, such as Australian psychiatrist Patrick McGorry, is risky because of a high rate of inaccuracy, the potential to stigmatize young people given this label, the lack of any effective treatment, and the risk of children and adolescents being given dangerous antipsychotic medication.[26] The elimination of the bereavement exclusion from the diagnosis of major depressive disorder was another particular concern, threatening to label normal grief as a mental illness. So while the task force was focusing on early detection and treatment, Frances cautioned about diagnostic inflation, overmedication, and crossing the boundary of normality. Besides the original complaint that the DSM-5 Task Force was a closed process, Frances pointed out that they were behind schedule and even with a one-year postponement, they had to drop a follow-up quality control step. He recommended further postponement and advocated asking an outside body to review their work to make suggestions. While the American Psychiatric Association did have an internal review, they rejected his suggestion of an external consultation. When the field testing for inter-rater reliability was released in May 2012, several of the more contested disorders were eliminated as unreliable[27] (attenuated psychosis syndrome, mixed anxiety depression) and the reliabilities were generally disappointing. The APA Board of Trustees eliminated a complex "Cross-Cutting" Dimensional System, but many of the contested areas remained when the document was approved for printing in December 2012 for a scheduled release in May 2013. There were widespread threats of a boycott.[28]

Frances's writings were joined by a general criticism of the DSM-5 revision, ultimately resulting in a petition calling for outside review signed by 14,000 and sponsored by 56 mental health organizations. In the course of almost three years of blogging, Frances became a voice for more than just the specifics of the DSM-5. He spoke out against the overuse of psychiatric medications—particularly in children; a general trend towards global diagnostic inflation—pathologizing normality; the intrusion of the pharmaceutical industry into psychiatric practice; and a premature attempt to move psychiatry to an exclusively biological paradigm without scientific justification. Along the way, he wrote two books: Saving Normal: An Insider's Revolt Against Out-of-Control Psychiatric Diagnosis, DSM-5, Big Pharma, and the Medicalization of Ordinary Life (2013), and Essentials of Psychiatric Diagnosis (2013), meant to guide clinicians and to help curb unwarranted diagnostic exuberance.[3][4] He has decided to continue writing on a new Psychology Today blog called Saving Normal.[29]

Major contentions[edit]

Neglecting severe mental illness[edit]

Frances contends that while the deinstitutionalization movement was needed due to hospital overcrowding, frequent civil liberties violations, and poor conditions for hospitalized psychiatric patients, its implementation in the United States was an utter failure. In 2018, he wrote,

The money saved from closing the custodial state hospitals was often misallocated to tax cuts and prison construction—depriving the mentally ill of adequate community treatment and housing. The result has been a broken American mental health "non-system" that overtreats the worried well and vastly undertreats the seriously mentally ill. Instead of 600,000 in state hospitals, we now have 350,000 mentally ill in prison and 250,000 homeless—because the vast majority is unable to obtain decent housing and access to treatment.[30]

Frances asserts that psychiatry itself has contributed to the neglect of the severely ill by diverting limited resources away from the community treatment of these patients and focusing instead on genetics research, neuroscience research, and the treatment of the mildly ill. He is particularly critical of NIMH spending excesses in the field of neuroscience, which he says have not helped a single patient in actual life.[31][32] He is a proponent of a community psychiatry approach.

He argues for the limited and safeguarded use of involuntary psychiatric hospitalization, writing that it is far preferable to the all-too-common alternatives: homelessness and imprisonment.[30]

Overtreating the worried well[edit]

Frances argues that with the gradual expansion of the DSM diagnostic system, psychiatry's attention has shifted away from the severely mentally ill and towards the treatment of the mildly ill or "worried well." This has led to several "false epidemics" of mental disorder, including autism and childhood bipolar disorder.[33] He writes extensively about the pathologization of normal human behavior in his book Saving Normal, and provides guidance to clinicians to avoid these pitfalls in Essentials of Psychiatric Diagnosis. During the DSM-5 revision process, he was particularly critical of the concepts of psychosis risk syndrome, binge eating disorder, and mild neurocognitive disorder.

Controversial treatments[edit]

Frances is a proponent of the safe and appropriate use of electroconvulsive therapy in severe and treatment-resistant cases of mental disorder; the use of lithium therapy for bipolar disorder; and the use of clozapine for schizophrenia.[34] Regarding electroconvulsive therapy, Frances argues that the treatment can be lifesaving in cases of severe, unrelenting depression and in some other psychiatric disorders, such as malignant, or lethal, catatonia. He has repeatedly asserted that if he were severely depressed, he would agree to electroconvulsive treatment.[35][36]

Frances has expressed his belief that both lithium carbonate and clozapine are underutilized in the treatment of bipolar disorder and schizophrenia,[34] respectively, often in favor of newer, more profitable second-generation antipsychotic drugs.[37] The current consensus in global psychiatry is that both lithium and clozapine remain the most effective agents in the treatment of their respective conditions; among academic psychiatrists, their underutilization is widely recognized.[38][39]

Frances has expressed skepticism over the use of ketamine in the treatment of clinical depression, writing that even if it is narrowly indicated in treatment-resistant mood disorder, "ketamine promotionals will encourage many people to start using it as self-medication for distress–a practice that is filled with risk and falls far outside any possible reasonable use of ketamine."[40]

On psychotherapy and psychoanalysis[edit]

Trained as a psychoanalyst, Frances taught the Freud course at the Columbia Psychoanalytic Center for a decade starting in the late 1970s. He has said that his "favorite work activity throughout [his] career was doing and teaching psychodynamic psychotherapy."[12] Some of his early work was on the study and treatment of personality disorder.

Frances contends that guild wars within psychotherapy have hurt the profession and those it treats; like Marvin Goldfried, he is a proponent of psychotherapy integration. He has said that the biggest mistake made by American psychoanalysis was their rejection of Aaron Beck's cognitive behavior therapy. Regarding Freud, Frances has said that Freud was "overvalued in his day and is now undervalued in ours."[12]

Biopsychosocial model[edit]

Frances is a proponent of George Engel's biopsychosocial model of mental disorder, writing that the "biopsychosocial model of mental illness and mental health care created a conceptual underpinning of psychiatric practice."[41] Frances is critical of reductionistic theories in psychiatry and psychology; in any mental disorder, biological, psychological, and social factors are working in tandem to create and maintain dysfunction.

Book and statements on Donald Trump[edit]

Frances wrote a 2017 book, titled, Twilight of American Sanity, in which he asserts that Trump himself does not suffer from a mental disease, but rather that the problem lies with the American people for selecting him as U.S. President.[7][6][5] Frances writes in the book: "Calling Trump crazy allows us to avoid confronting the craziness in our society."[5] The Washington Post gave a book review of Twilight of American Sanity and found the arguments by Frances to stray from medical to political in nature.[5] The book review by Carlos Lozada in The Washington Post concluded: "America is delusional not just because it elected Trump, but because it doesn’t conform to Frances’s views on climate change, population growth, technology, privacy, war, economics and guns."[5] Publishers Weekly concluded in a book review that Twilight of American Sanity contained factual errors and exaggeration.[7] A book review by Kirkus Reviews was positive, calling the work a "cogent analysis".[6] Kirkus Reviews concluded its book review: "This welcome and insightful book joins a small shelf of essential titles ... that help explain why and how the Trump presidency happened."[6]

On August 25, 2019, in an interview on CNN, Frances stated that Trump may wind up being responsible for millions of deaths and may wind up killing more people than Adolf Hitler, Joseph Stalin and Mao Zedong.[42][43][44] Frances was quoted as saying, "Trump is as destructive a person in this century, as Hitler, Stalin, and Mao were in the last century. He may be responsible for many more million deaths than they were. He needs to be contained, but he needs to be contained by attacking his policies, not his person."[42][43][44]

Politifact noted that Frances posted a follow-up to Twitter in which he asserted his comments referred to the potential future impact of climate change.[42] Politifact brought forth multiple referenced sources in order to analyze the comments by Frances.[42] Politifact reported that according to Timothy Snyder, Yale University history professor in a 2011 calculation, Adolf Hitler killed over eleven million people during the Holocaust.[42] Politifact noted that the U.S. Holocaust Memorial Museum estimated about 17 million deaths attributed to Hitler during World War II.[42] Politifact cited the book The Souls of China: The Return of Religion After Mao by author Ian Johnson, which found Mao Zedong responsible for approximately 42.5 million fatalities.[42]

Politifact wrote in their analysis: "Not only does Frances’ comparison exaggerate the predicted climate change death toll compared to that of the dictators, he also lays the blame for potential future deaths at Trump's feet alone, which even experts critical of Trump consider wrongheaded."[42] Politifact concluded, "We rate the statement Pants on Fire.[42]

Snopes analyzed the assertions by Frances and received a follow-up comment from him, in response to social media backlash to his statements.[43] Frances clarified in his comment to Snopes, that he was referring to the potential future impact of climate change.[43] Frances said in his email to Snopes: "I think it is no exaggeration to worry that the policies that follow from Trump’s reckless climate denial may wind up causing the death of hundreds of millions of people. Our species appears to be on a path to self-destruction, and Trump is enthusiastically leading the way."[43]

References[edit]

  1. ^ a b Siris, Samuel G. (August 1, 2006), "Differential Therapeutics in Psychiatry: The Art and Science of Treatment Selection—by Allen Frances, M.D., John Clarkin, Ph.D., and Samuel Perry, M.D.; Brunner/Mazel, New York, 1984, 395 pages, $30", Psychiatric Services, 36 (6): 669, doi:10.1176/ps.36.6.669
  2. ^ a b "Your Mental Health: A Layman's Guide to the Psychiatrist's Bible", WorldCat, OCLC, 2019, OCLC 605729701
  3. ^ a b Guldberg, Helene (July 16, 2014), "Review: Saving Normal - A rebellion against the pathologisation of everyday life.", Psychology Today, retrieved August 27, 2019
  4. ^ a b Pierre, Joseph M. (June 27, 2014), "Essentials of Psychiatric Diagnosis: Responding to the Challenge of DSM-5", Psychiatric Times, 31 (6), retrieved August 27, 2019
  5. ^ a b c d e Lozada, Carlos (September 22, 2017), "Book Party - Review - Is Trump mentally ill? Or is America? Psychiatrists weigh in.", The Washington Post, retrieved August 27, 2019
  6. ^ a b c d "Book Review - Twilight of American Sanity", Kirkus Reviews, August 7, 2017, retrieved August 27, 2019
  7. ^ a b c "Nonfiction Book Review - Twilight of American Sanity: A Psychiatrist Analyzes the Age of Trump", Publishers Weekly, October 2017, retrieved August 27, 2019
  8. ^ "Live Internet Talk Radio Shows Streaming On-line | Listen for Free". VoiceAmerica. Retrieved August 17, 2017.
  9. ^ "Bookshelf". Columbia College Today. Fall 2018. Retrieved June 7, 2020.
  10. ^ a b c Frances, Allen James, Duke University, Duke Psychiatry & Behavioral Sciences; Duke University School of Medicine, 2019, retrieved August 28, 2019
  11. ^ "Allen Frances, MD '67 - 'Saving Normal: Over Treatment in Psychiatry'" (PDF), Alumni Reunion Brochure 2017, SUNY Downstate College of Medicine, 2017, retrieved August 28, 2019
  12. ^ a b c "Allen Frances: Portrait of the Psychiatrist as a Young Man". Psychology Today. Retrieved April 12, 2021.
  13. ^ "Allen Frances, M.D.", The Huffington Post, Verizon Media, 2019, retrieved August 28, 2019
  14. ^ a b Rubin, Lawrence (2019), "Allen Frances on the DSM-5, Mental Illness and Humane Treatment", Psychotherapy.net: Great Therapists Never Stop Learning, retrieved August 28, 2019
  15. ^ Frances, Allen; Clarkin,JF (May 1981). "No Treatment as the Prescription of Choice". Arch Gen Psychiatry. 38 (5): 542–545. doi:10.1001/archpsyc.1980.01780300054006. PMID 7235855.
  16. ^ a b Frances, Allen (August 6, 2013). "The new crisis of confidence in psychiatric diagnosis". Annals of Internal Medicine. 159 (2): 221–222. doi:10.7326/0003-4819-159-3-201308060-00655. PMID 23685989.
  17. ^ Frances, Allen (January 2013). "The past, present and future of psychiatric diagnosis". World Psychiatry. 12 (2): 111–112. doi:10.1002/wps.20027. PMC 3683254. PMID 23737411.
  18. ^ David J. Kupfer; Michael B. First; Darrel A. Regier, eds. (2002). A Research Agenda For DSM V A Research Agenda For DSM V. Arlington, VA: American Psychiatric Publishing. p. 336. ISBN 978-0-89042-292-2.
  19. ^ Spitzer, Robert (June 18, 2008). "DSM-V: Open and Transparent?". Psychiatric News. Retrieved March 26, 2013.
  20. ^ Greenberg, Gary. "Inside the Battle to Define Mental Illness". Wired. Retrieved March 26, 2013.
  21. ^ Frances, Allen (June 26, 2009). "A Warning Sign on the Road to DSM-V: Beware of Its Unintended Consequences". Psychiatric Times. Retrieved March 26, 2013.
  22. ^ Schatzberg AF, Scully JH, Kupfer DJ, Regier DA (July 1, 2009). "Setting the Record Straight: A Response to Frances Commentary on DSM-V". Psychiatric Times. Retrieved March 26, 2013.
  23. ^ Frances, Allen. "DSM5 in Distress: The DSM's impact on mental health practice and research". Psychology Today. Retrieved March 26, 2013.
  24. ^ Frances, Allen. "Blog". Psychiatric Times. Retrieved March 26, 2013.
  25. ^ Frances, Allen. "Blog". The Huffington Post. Retrieved March 26, 2013.
  26. ^ "Frances A. Psychosis risk syndrome—far too risky". Aust N Z J Psychiatry. 2011 Oct;45(10):803-4.
  27. ^ Carey, Benedict (May 8, 2012). "Psychiatry Manual Drafters Back Down on Diagnoses". New York Times. Retrieved March 27, 2013.
  28. ^ Carney, Jack (February 5, 2013), "DSM-5 Boycott Launched!", Mad in America, retrieved August 27, 2019
  29. ^ Frances, Allen. "Saving Normal: Mental health and what is normal". Psychology Today. Retrieved March 26, 2013.
  30. ^ a b "Mental Illness, Civil Liberty, and Common Sense". Psychiatric Times. Retrieved April 17, 2021.
  31. ^ "The lure of 'cool' brain research is stifling psychotherapy – Allen Frances | Aeon Ideas". Aeon. Retrieved April 17, 2021.
  32. ^ "https://twitter.com/allenfrancesmd/status/1099020070200569862". Twitter. Retrieved April 17, 2021. External link in |title= (help)
  33. ^ Frances, Allen (2013). Saving Normal. HarperCollins.
  34. ^ a b "Advice to Young Psychiatrists From a Very Old One". Psychiatric Times. Retrieved April 17, 2021.
  35. ^ "https://twitter.com/allenfrancesmd/status/1268245036673626112". Twitter. Retrieved April 17, 2021. External link in |title= (help)
  36. ^ "https://twitter.com/allenfrancesmd/status/879760641245892608". Twitter. Retrieved April 17, 2021. External link in |title= (help)
  37. ^ Allen J. Frances on the overdiagnosis of mental illness, retrieved April 17, 2021
  38. ^ Post, Robert M (April 2018). "The New News about Lithium: An Underutilized Treatment in the United States". Neuropsychopharmacology. 43 (5): 1174–1179. doi:10.1038/npp.2017.238. ISSN 0893-133X. PMC 5854802. PMID 28976944.
  39. ^ Bogers, Jan P. A. M.; Schulte, Peter F. J.; Van Dijk, Daniel; Bakker, Bert; Cohen, Dan (April 2016). "Clozapine Underutilization in the Treatment of Schizophrenia: How Can Clozapine Prescription Rates Be Improved?". Journal of Clinical Psychopharmacology. 36 (2): 109–111. doi:10.1097/JCP.0000000000000478. ISSN 0271-0749. PMID 26872120.
  40. ^ "Is Ketamine Really a Miracle Drug for Depression?". Drug Rehab Options. Retrieved April 17, 2021.
  41. ^ Frances, Allen (December 1, 2014). "Resuscitating the biopsychosocial model". The Lancet Psychiatry. 1 (7): 496–497. doi:10.1016/S2215-0366(14)00058-3. ISSN 2215-0366. PMID 26361297.
  42. ^ a b c d e f g h i Jacobson, Louis (August 26, 2019). "Hitler, Stalin, Mao ... and Trump? No, Pants on Fire". Politifact. Poynter Institute. Retrieved August 27, 2019.
  43. ^ a b c d e Palma, Bethania (August 27, 2019), "Did a Psychiatrist Say Trump May Cause More Deaths Than Hitler, Stalin, and Mao?", Snopes, retrieved August 27, 2019
  44. ^ a b Givas, Nick (August 25, 2019). "Duke professor compares 'destructive' Trump to 'Hitler, Stalin and Mao' during CNN interview". FOX News. Retrieved August 26, 2019.

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