Alopecia universalis

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Alopecia universalis
Classification and external resources
Specialty dermatology
ICD-10 L63.1

Alopecia universalis or alopecia areata universalis is a medical condition involving rapid loss of all hair, including eyebrows and eyelashes. It is the most severe form of alopecia areata, with an incidence of .0005% (1 in 200,000).[1][unreliable medical source?]


Alopecia universalis can occur at any age, and is currently believed to be an autoimmune disorder.[2]


There is no standard treatment for alopecia universalis. Spontaneous regrowth is always a possibility, even for those with 100% hair loss over many years. However, it is not possible to predict when regrowth will occur.[3][unreliable medical source?] Many treatments have been explored, including immunomodulatory agents such as imiquimod.[4] Tofacitinib citrate may also have benefits. In June 2014, it was reported that a 25-year-old man with almost no hair on his body grew a full head of hair, and eyebrows, eyelashes, facial, armpit and other hair, following 8 months of treatment.[5]

See also[edit]


  1. ^
  2. ^ Robins DN (2007). "Case reports: alopecia universalis: hair growth following initiation of simvastatin and ezetimibe therapy". Journal of drugs in dermatology : JDD 6 (9): 946–7. PMID 17941369. 
  3. ^
  4. ^ Letada PR, Sparling JD, Norwood C (2007). "Imiquimod in the treatment of alopecia universalis". Cutis; cutaneous medicine for the practitioner 79 (2): 138–40. PMID 17388216. 
  5. ^

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