Alopecia universalis

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Alopecia universalis
Classification and external resources
Specialty dermatology
ICD-10 L63.1

Alopecia universalis (AU) or alopecia areata universalis is a medical condition involving rapid loss of all hair, including eyebrows and eyelashes. It is an advanced form of Alopecia areata.[1]

Causes[edit]

Alopecia universalis can occur at any age, and is currently believed to be an autoimmune disorder, in which a person's immune system attacks the hair follicles. Genetic factors may contribute to AU as approximately 20% of those affected have a family member with alopecia.[2][3]

Treatment[edit]

There is no standard treatment for alopecia universalis. Many treatments have been explored, including immunomodulatory agents such as imiquimod.[4] Tofacitinib citrate may also have benefits. In June 2014, it was reported that a 25-year-old man with almost no hair on his body grew a full head of hair, and eyebrows, eyelashes, facial, armpit and other hair, following 8 months of treatment.[5]

See also[edit]

References[edit]

  1. ^ "Alopecia universalis | Disease | Overview | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 2016-03-01. 
  2. ^ Robins DN (2007). "Case reports: alopecia universalis: hair growth following initiation of simvastatin and ezetimibe therapy". Journal of drugs in dermatology : JDD 6 (9): 946–7. PMID 17941369. 
  3. ^ "Alopecia universalis | Disease | Overview | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 2016-03-01. 
  4. ^ Letada PR, Sparling JD, Norwood C (2007). "Imiquimod in the treatment of alopecia universalis". Cutis; cutaneous medicine for the practitioner 79 (2): 138–40. PMID 17388216. 
  5. ^ "Hairless Man Grows Full Head Of Hair In Yale Arthritis Drug Trial". boston.cbslocal.com. 

External links[edit]