Alpha-3 beta-2 nicotinic receptor

From Wikipedia, the free encyclopedia
Jump to: navigation, search

The alpha-3 beta-2 nicotinic receptor, also known as the α3β2 receptor, is a type of nicotinic acetylcholine receptor, consisting of α3 and β2 subunits.

Ligands[edit]

Agonists[edit]

PAMs[edit]

Antagonists[edit]

See also[edit]

References[edit]

  1. ^ a b c d e f g h i Chavez-Noriega LE, Gillespie A, Stauderman KA, et al. (October 2000). "Characterization of the recombinant human neuronal nicotinic acetylcholine receptors alpha3beta2 and alpha4beta2 stably expressed in HEK293 cells". Neuropharmacology. 39 (13): 2543–60. doi:10.1016/s0028-3908(00)00134-9. PMID 11044726. 
  2. ^ Mihalak KB, Carroll FI, Luetje CW (September 2006). "Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors". Mol. Pharmacol. 70 (3): 801–5. doi:10.1124/mol.106.025130. PMID 16766716. 
  3. ^ Levandoski MM, Piket B, Chang J (June 2003). "The anthelmintic levamisole is an allosteric modulator of human neuronal nicotinic acetylcholine receptors". Eur. J. Pharmacol. 471 (1): 9–20. doi:10.1016/s0014-2999(03)01796-5. PMID 12809947. 
  4. ^ Seo S, Henry JT, Lewis AH, Wang N, Levandoski MM (July 2009). "The positive allosteric modulator morantel binds at noncanonical subunit interfaces of neuronal nicotinic acetylcholine receptors". J. Neurosci. 29 (27): 8734–42. doi:10.1523/JNEUROSCI.1859-09.2009. PMC 2726771Freely accessible. PMID 19587280. 
  5. ^ Crooks PA, Bardo MT, Dwoskin LP (2014). "Nicotinic receptor antagonists as treatments for nicotine abuse". Adv. Pharmacol. 69: 513–51. doi:10.1016/B978-0-12-420118-7.00013-5. PMC 4110698Freely accessible. PMID 24484986. 
  6. ^ Lee RH, Tseng TY, Wu CY, et al. (2012). "Memantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteries". PLoS ONE. 7 (7): e40326. doi:10.1371/journal.pone.0040326. PMC 3390354Freely accessible. PMID 22792283.