alpha-Zearalenol

From Wikipedia, the free encyclopedia
  (Redirected from Alpha-zearalenol)
Jump to navigation Jump to search
α-Zearalenol
Alpha Zearalenol.svg
Clinical data
Synonyms alpha-Zearalenol; trans-Zearalenol; 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
Formula C18H24O5
Molar mass 320.3802 g/mol
3D model (JSmol)

α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.[1] It is the α epimer of β-zearalenol and along with β-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.[2][3] A relatively low proportion of β-zearalenol is formed from zearalenone compared to α-zearalenol in humans.[3] α-Zearalenol is about 3- to 4-fold more potent as an estrogen relative to zearalenone.[1]

See also[edit]

References[edit]

  1. ^ a b J. Chelkowski (28 June 2014). Fusarium: Mycotoxins, Taxonomy, Pathogenicity. Elsevier Science. pp. 85–. ISBN 978-1-4832-9785-9. 
  2. ^ Naresh Magan; Monica Olsen (2004). Mycotoxins in Food: Detection and Control. Woodhead Publishing. pp. 356–. ISBN 978-1-85573-733-4. 
  3. ^ a b G. S. Eriksen (1998). Fusarium Toxins in Cereals: A Risk Assessment. Nordic Council of Ministers. pp. 61–. ISBN 978-92-893-0149-7.