Amalia, who had two sisters, Emma and Erminia, and a brother, Ernesto, was born in Turin to Pietro Guglielminetti and his wife Felicita Lavezzato. Her great-grandfather had moved from Cravanzana to Turin around 1858, where he had established a timber business. He invented a water canteen, at that time made of wood, which became popular. Her father died in 1886, and the family moved in with a grandfather, who sent Amalia to a religious school.
She started writing in 1901 for the "Gazzetta del Popolo", where her poetry was published in the Sunday supplement. Her poetry then appeared in Voci di Giovinezza, published in 1903, and was dedicated to her father.
Her main works are the poetry collections Le seduzioni (1908) and L'insonne (1913) and the prose collections I volti dell'amore (1913) and Quando avevo un amante (1923).
Between 1916 and 1925 she wrote books for children: Fiabe in versi (1916); La reginetta Chiomadoro (1923); Il ragno incantato (1923) and La carriera dei pupazzi (1925).
In the following years she became romantically involved with Pitigrilli (Dino Segre). The relationship became so intense that she had a nervous breakdown. She eventually recovered, and felt that the experience had made her stronger.
She died from complications resulting from an accident during an air-raid. She had always been a solitary and somewhat depressed figure.
- Benso, Ornella: Una relazione letteraria. Amalia Guglielminetti e Guido Gozzano, Turín, 1944.
- Gastaldi, M.: Amalia Guglielminetti, Milán, 1930.
- Guglielminetti, Marziano: La Musa subalpina. Amalia e Guido, Pastonchi e Pitigrilli, Florencia, L. S. Olschki, 2007.
- Ferraro, Alessandro: La corsa del levriero. Amalia Guglielminetti nel Novecento italiano, in Amalia Guglielminetti, La rivincita del maschio, edit by Alessandro Ferraro, Genova, Sagep, 2014.
- Ferraro, Alessandro: Il frutto dietro la foglia. 1928 e 1934: Amalia Guglielminetti denunciata due volte per oltraggio al pudore, «Nuova Corrente», LXII, 155, 2015.
- Ferraro, Alessandro: Amalia Guglielminetti. Le opere, la vita (1881-1941), Genova, 2016.
- Rota, Marina: Amalia, se Voi foste uomo..., Torino, Golem, 2016
- Italia Donne (2009). "Amalia Guglielminetti". Biography (in Italian). Feltrinelli. Archived from the original on 28 January 2010. Retrieved 1 March 2010.
- Guglielminetti, Amalia (1941), "Come nacque la borraccia (How the canteen was born)", La Lettura (in Italian)
- Lettere d'amore, G. Gozzano e A. Guglielminetti, 1951)