Amanullinic acid

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Amanullinic acid
Amanullinic acid structure.png
Amanullinic acid with tube model.png
Names
Other names
1-L-Aspartic acid-3-isoleucine-alpha-amanitin
Identifiers
54532-45-5 YesY
ChemSpider 149798 YesY
Jmol-3D images Image
Image
PubChem 171349
Properties
C39H53N9O13S
Molar mass 887.96 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 YesY verify (what isYesY/N?)
Infobox references

Amanullinic acid is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the Amanita genus of mushrooms. The oral LD50 of amanullinic acid is approximately 0.1 mg/kg in mice.[1]

Toxicology[edit]

Like other amatoxins, amanullinic acid is an inhibitor of RNA polymerase II.

See also[edit]

References[edit]

  1. ^ T. Wieland and Faulstich H. (1978). "Amatoxins, Phallotoxins, Phallolysin, and Antamanide: the Biologically Active Components of Poisonous Amanita Mushrooms". CRC Critical Reviews in Biochemistry 5 (3): 185–260. doi:10.3109/10409237809149870. PMID 363352. 

External links[edit]