Ambrosia psilostachya is an erect perennial herb growing a slender, branching, straw-colored stem to a maximum height near two meters, but more often remaining under one meter tall. Leaves are up to 12 centimeters long and vary in shape from lance-shaped to nearly oval, and they are divided into many narrow, pointed lobes. The stem and leaves are hairy.
The top of the stem is occupied by an inflorescence which is usually a spike. The species is monoecious, and the inflorescence is composed of staminate (male) flower heads with the pistillate heads located below and in the axils of leaves. This bloom period is from June through November.
The pistillate heads yield fruits which are achenes located within oval-shaped greenish-brown burs about half a centimeter long. The burs are hairy and sometimes spiny. The plant reproduces by seed and by sprouting up from a creeping rhizome-like root system.
This plant had a number of medicinal uses among several different Native American tribes, including the Cheyenne, Kumeyaay (Diegueno), and Kiowa people.  It contains a biologically active phytochemical called Psilostachyin.
- The International Plant Names Index
- The Plant List Ambrosia psilostachya DC.
- "BSBI List 2007" (xls). Botanical Society of Britain and Ireland. Archived from the original on 2015-01-25. Retrieved 2014-10-17.
- Biota of North America Program 2104 county distribution map
- United States Department of Agriculture Plants Profile . accessed 2.14.2013
- Flora of North America Vol. 21 Page 18 Ambrosia psilostachya de Candolle in A. P. de Candolle and A. L. P. P. de Candolle
- Flora of China Vol. 20-21 Page 877 裸穗豚草 luo sui tun cao Ambrosia psilostachya Candolle
- Tropicos, specimen listing for Ambrosia psilostachya DC
- Altervista Flora Italiana, Ambrosia con spighe rade, Ambrosia psilostachya DC. includes photos and European distribution map
- Atlas of Living Australia, Ambrosia psilostachya DC. Perennial Ragweed
- Neill, Robert L.; Rice, Elroy L. (October 1971). "Possible Role of Ambrosia psilostachya on Pattern and Succession in Old-Fields". American Midland Naturalist. 86 (2): 344–57. doi:10.2307/2423628. JSTOR 2423628.
- University of Michigan at Dearborn: Native American Ethnobotany of Ambrosia psilostachya . accessed 2.14.2013
- Wan, Shiqiang; Yuan, Tong; Bowdish, Sarah; Wallace, Linda; Russell, Scott D.; Luo, Yiqi (2002). "Response of an allergenic species, Ambrosia psilostachya (Asteraceae), to experimental warming and clipping: Implications for public health". American Journal of Botany. 89 (11): 1843–6. doi:10.3732/ajb.89.11.1843. PMID 21665612.
- USDA Plants Profile for Ambrosia psilostachya (Cooper's popcornflower)
- Calflora Database: Ambrosia psilostachya (Western ragweed)
- Jepson Manual eFlora (TJM2) treatment: Ambrosia psilostachya
- USDA National Forest Service, FEIS Ecology of Ambrosia psilostachya
- USGS.gov: Northern Prairie Wildlife Profile
- UC Calphotos Photos gallery of Ambrosia psilostachya
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