Amdoparvovirus

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Amdoparvovirus
Virus classification
Group: Group II (ssDNA)
Family: Parvoviridae
Subfamily: Parvovirinae
Genus: Amdoparvovirus
Species

Amdoparvovirus is a genus of viruses, in the family Parvoviridae, in the subfamily Parvovirinae. Mustelids (minks, ferrets, and foxes), skunk, and raccoons serve as natural hosts. There are currently only two species in this genus including the type species Carnivore amdoparvovirus 1 (Aleutian mink disease virus). Diseases associated with this genus include: progressive disorder of immune system.[1][2][3][4][5]

Taxonomy[edit]

Group: ssDNA

[2]

Structure[edit]

Viruses in Amdoparvovirus are non-enveloped, with icosahedral and Round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 4.8kb in length. [1]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Amdoparvovirus Icosahedral T=1 Non-enveloped Linear None

Life cycle[edit]

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus may exit the host cell by vesicular trafficking following nuclear pore export or be released following cell lysis. Mustelids, skunk, and raccoons serve as the natural host. Transmission routes are oral and respiratory.

[1]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Amdoparvovirus Mammals: minks, ferrets, foxes None Clathrin-mediated endocytosis vesicular export or cell lysis Nucleus Nucleus Unknown

References[edit]

  1. ^ a b c "Viral Zone". ExPASy. Retrieved 12 June 2015. 
  2. ^ a b ICTV. "Virus Taxonomy: 2014 Release". Retrieved 12 June 2015. 
  3. ^ Cheng, F.; Chen, A. Y.; Best, S. M.; Bloom, M. E.; Pintel, D.; Qiu, J. (2009). "The Capsid Proteins of Aleutian Mink Disease Virus Activate Caspases and Are Specifically Cleaved during Infection". Journal of Virology. 84 (6): 2687–2696. PMC 2826067Freely accessible. PMID 20042496. doi:10.1128/JVI.01917-09. 
  4. ^ Li, L.; Pesavento, P. A.; Woods, L.; Clifford, D. L.; Luff, J.; Wang, C.; Delwart, E. (2011). "Novel Amdovirus in Gray Foxes". Emerging Infectious Diseases. 17 (10): 1876–1878. PMC 3310670Freely accessible. PMID 22000359. doi:10.3201/eid1710.110233. 
  5. ^ Canuti, Marta; Whitney, Hugh G.; Lang, Andrew S. (2015-01-01). "Amdoparvoviruses in small mammals: expanding our understanding of parvovirus diversity, distribution, and pathology". Virology: 1119. doi:10.3389/fmicb.2015.01119. 

External links[edit]