3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||g·mol−1 111.037|
|Melting point||338 to 344 °C (640 to 651 °F; 611 to 617 K)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Aminomethylphosphonic acid (AMPA) is a weak organic acid with a phosphonic acid group. It is one of the primary degradation products of the herbicide glyphosate. AMPA has toxicity which is comparable to that of glyphosate and it is therefore considered to be of similar toxicological concern as (harmful in greater than 0.5 parts per billion) glyphosate itself. AMPA has the potential to be broken down further by manganese oxide in laboratory conditions, however in soil manganese oxide is usually only present in trace amounts. Microbial degradation of AMPA is the more likely degradation pathway, where it degrades into phosphoric acid  and ultimately to carbon dioxide and inorganic phosphate.
- Environmental Fate of Glyphosate, Jeff Schuette, Department of Pesticide Regulation, California
- Pesticide Residues in Food - 1997, FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group
- K. A. Barrett and M. B. McBride. Oxidative Degradation of Glyphosate and Aminomethylphosphonate by Manganese Oxide. Environ. Sci. Technol., 2005, 39 (23), pp 9223–9228
- Pipke R, Amrhein N. (1988) Isolation and characterization of a mutant of Arthrobacter sp. strain GLP-1 which utilizes the herbicide glyphosate as its sole source of phosphorus and nitrogen. Applied and Environmental Microbiology 54(11): 2868-2870.
- Forlani G, Mangiagalli A, Nielsen E, Suardi CM. (1999) Degradation of the phosphonate herbicide glyphosate in soil: Evidence for a possible involvement of unculturable microorganisms. Soil Biology and Biochemistry 31: 991-997
- Backgrounder: Glyphosate does not degrade to phosphorous acid in the environment. Monsanto. 2005