Aminopeptidase Y

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Aminopeptidase Y
4x8i.jpg
Lysyl aminopeptidase dodekamer, Pyrococcus furiosus
Identifiers
EC number3.4.11.15
CAS number114796-97-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Aminopeptidase Y (EC 3.4.11.15, aminopeptidase Co, aminopeptidase (cobalt-activated), lysyl aminopeptidase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Preferentially, release of N-terminal lysine

This enzyme requires Co2+. It is inhibited by Zn2+ and Mn2+.

References[edit]

  1. ^ Achstetter T, Ehmann C, Wolf DH (November 1982). "Aminopeptidase Co, a new yeast peptidase". Biochemical and Biophysical Research Communications. 109 (2): 341–7. doi:10.1016/0006-291x(82)91726-0. PMID 6758786.
  2. ^ Yasuhara T, Nakai T, Ohashi A (May 1994). "Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B". The Journal of Biological Chemistry. 269 (18): 13644–50. PMID 8175799.
  3. ^ Nishizawa M, Yasuhara T, Nakai T, Fujiki Y, Ohashi A (May 1994). "Molecular cloning of the aminopeptidase Y gene of Saccharomyces cerevisiae. Sequence analysis and gene disruption of a new aminopeptidase". The Journal of Biological Chemistry. 269 (18): 13651–5. PMID 8175800.

External links[edit]