Aminopeptidase Y

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Aminopeptidase Y
4x8i.jpg
Lysyl aminopeptidase dodekamer, Pyrococcus furiosus
Identifiers
EC number 3.4.11.15
CAS number 114796-97-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Aminopeptidase Y (EC 3.4.11.15, aminopeptidase Co, aminopeptidase (cobalt-activated), lysyl aminopeptidase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Preferentially, release of N-terminal lysine

This enzyme requires Co2+. It is inhibited by Zn2+ and Mn2+.

References[edit]

  1. ^ Achstetter, T.; Ehmann, C.; Wolf, D.H. (1982). "Aminopeptidase Co, a new yeast peptidase". Biochem. Biophys. Res. Commun. 109: 341–347. doi:10.1016/0006-291x(82)91726-0. PMID 6758786. 
  2. ^ Yasuhara, T.; Nakai, T.; Ohashi, A. (1994). "Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B". J. Biol. Chem. 269: 13644–13650. PMID 8175799. 
  3. ^ Nishizawa, M.; Yasuhara, T.; Nakai, T.; Fujiki, Y.; Ohashi, A. (1994). "Molecular cloning of the aminopeptidase Y gene of Saccharomyces cerevisiae. Sequence analysis and gene disruption of a new aminopeptidase". J. Biol. Chem. 269: 13651–13655. PMID 8175800. 

External links[edit]