Aminophenazone

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Aminophenazone
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Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Pharmacokinetic data
Metabolism N-demethylation[1]
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.000.332
Chemical and physical data
Formula C13H17N3O
Molar mass 231.29358
3D model (Jmol)
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Aminophenazone (or aminopyrine) is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of agranulocytosis. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of cytochrome P-450 metabolic activity in liver function tests.[1] It is also used in measuring the total body water in the human body system.[2]

References[edit]

  1. ^ a b Caubet, M. S.; Laplante, A.; Caillé, J.; Brazier, J. L. (4 Jan 2007). "[13C]Aminopyrine and [13C]Caffeine Breath Test: Influence of Gender, Cigarette Smoking and Oral Contraceptives Intake". Isotopes in Environmental and Health Studies. 38 (2): 71–77. doi:10.1080/10256010208033314. 
  2. ^ "Aminophenazone — Compound Summary". PubChem. The National Library of Medicine. 2005-03-26. Retrieved June 12, 2008.