Amotivational syndrome

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Person subject to amotivational syndrome

Amotivational syndrome is characterized by detachment, blunted emotion and drives, and executive functions like memory and attention are impaired; it is primarily associated with long-term effects of cannabis use.[1] Pacheco-Colón et al. (2018) concludes:[2]

In conclusion, studies examining the effects of cannabis use on motivation and reward sensitivity have yielded mixed findings. We conclude that cross-sectional evidence supporting the presence of amotivational syndrome among cannabis users or an adverse cannabis-specific effect on motivation is currently equivocal.

— Pacheco-Colón et al.

According to the Handbook of Clinical Psychopharmacology for Therapists, amotivational syndrome is listed as a possible side effect of SSRIs in the treatment of clinical depression.[3]

See also[edit]


  1. ^ Rovai, L; Maremmani, AG; Pacini, M; Pani, PP; Rugani, F; Lamanna, F; Schiavi, E; Mautone, S; Dell'Osso, L; Maremmani, I (2013). "Negative dimension in psychiatry. Amotivational syndrome as a paradigm of negative symptoms in substance abuse". Rivista di psichiatria. 48 (1): 1–9. doi:10.1708/1228.13610. PMID 23438696. open access
  2. ^ Pacheco-Colón I, Limia JM, Gonzalez R (August 2018). "Nonacute effects of cannabis use on motivation and reward sensitivity in humans: A systematic review". Psychol Addict Behav. 32 (5): 497–507. doi:10.1037/adb0000380. PMID 29963875.
  3. ^ Preston, John; John, O'Neal; Mary, Talaga (2013). Handbook of Clinical Psychopharmacology for Therapists (7th ed.). New Harbinger Publications. p. 193. ISBN 1608826643.