Amphicleia or Amphicaea (in Greek Aμφίκλεια or Aμφίκαια) was an ancient Greek town in the North of Phocis, distant 60 stadia from Lilaea, and 15 stadia from Tithronium. It was destroyed by the Persian army of Xerxes in his invasion of Greece (480 BC). Although Herodotus calls it Amphicaea, following the most ancient traditions, the Amphictyonic League gave it the name of Amphicleia in their decree respecting rebuilding the town (346 BC). It also bore for some time the name of Ophiteia, in consequence of a legend, which Pausanias relates. The place was celebrated in the time of Pausanias for the worship of Dionysus, to which an inscription refers, found at the site of the ancient town. The same site is now occupied by the modern town of Amfikleia.