Amy Rosenzweig

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Amy Rosenzweig
Fields biochemistry
Institutions Northwestern University
Alma mater Amherst College, Massachusetts Institute of Technology
Doctoral advisor Stephen J. Lippard
Notable awards MacArthur Fellows Program

Amy C. Rosenzweig is an American biochemist, professor of Chemistry, Biochemistry, Molecular Biology and Cell Biology, at Northwestern University.[1][2][3]

She graduated from Amherst College with a B.A. in 1988, and Massachusetts Institute of Technology with a Ph.D. in 1994, after working with Stephen J. Lippard. She determined the crystal structure of methane monooxygenase, beginning with a publication in Nature in 1993.[4][5] She has contributed significantly to the understanding of the methane and the structures involved in the enzymatic oxidation of methane to methanol.[6]



  • Lieberman, R. L & Rosenzweig, A. C. "Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane", Nature 2005, 434, 177-182.
  • Lieberman, R. L., Kondapalli, K. C., Shrestha, D. B., Hakemian, A. S., Smith, S. M., Telser, J., Kuzelka, J., Gupta, R., Borovik, A. S., Lippard, S. J., Hoffman, B. M., Rosenzweig, A. C., & Stemmler, T. L. "Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy". Inorg. Chem. 2006, 45, 8372-8381.
  • Sazinsky, M. H., Mandal, A. L, Argüello, J. M., & Rosenzweig, A. C. "Structure of the ATP binding domain from the Archaeglobus fulgidus Cu1+-ATPase". J. Biol. Chem.. 2006, 281, 11161-11166.
  • Yatsunyk, L. A. & Rosenzweig, A. C. "Copper binding and transfer by the N-terminus of the Wilson disease protein", J. Biol. Chem.. 2007, 282, 8622-8631.
  • Rosenzweig, Lippard, "Structure and Biochemistry Methane Monooxygenase Enzyme Systems", Transition metals in microbial metabolism, Editors Günther Winkelmann, Carl J. Carrano, CRC Press, 1997, ISBN 978-90-5702-220-3
  • Rosenzweig, Feng, Lippard, "Studies of Methane Monooxygenase and Alkane Oxidation Model Complexes", Applications of enzyme biotechnology, Editors Jeffery W. Kelly, Thomas O. Baldwin, Springer, 1991, ISBN 978-0-306-44095-3


  1. ^ Amy Rosenzweig :: Faculty :: IBiS Graduate Program
  2. ^ "Archived copy". Archived from the original on 2010-06-20. Retrieved 2010-04-17. 
  3. ^
  4. ^ Halford, Bethany (March 17, 2014). "Trailblazer And Mentor". Chemical & Engineering News. 92 (11). Retrieved 24 March 2017. 
  5. ^ Rosenzweig, Amy C.; Frederick, Christin A.; Lippard, Stephen J.; Nordlund, Pär (9 December 1993). "Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane". Nature. 366 (6455): 537–543. doi:10.1038/366537a0. Retrieved 24 March 2017. 
  6. ^ Rosenzweig, Amy C. (21 January 2015). "Biochemistry: Breaking methane". Nature. 518 (7539): 309–310. doi:10.1038/nature14199. Retrieved 24 March 2017. 

External links[edit]