Amylocaine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Amylocaine
Amylocaine.png
Names
IUPAC name
benzoic acid [1-(dimethylaminomethyl)-1-methylpropyl] ester
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.010.375
KEGG
UNII
Properties
C14H21NO2
Molar mass 235.32204
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Amylocaine was the first synthetic local anesthetic. It was synthesized and patented under the name Stovaine by Ernest Fourneau at the Pasteur Institute in 1903.[1] It used to be used mostly in spinal anesthesia.[2]

Notes and references[edit]

  1. ^ Fourneau, E. (1904). "Stovaïne, anesthésique local". Bulletin des sciences pharmacologiques. 10: 141-148.
  2. ^ Debue-Barazer, Christine (2007). "Les Implications scientifiques et industrielles du succès de la Stovaïne : Ernest Fourneau (1872-1949) et la chimie des médicaments en France". Gesnerus 64 (1-2): 24-53.

See also[edit]

External links[edit]

  • Smith, Maurice I.; Hatcher, Robert A. (January 1917). "A Contribution to the Pharmacology of Stovaine". Journal of Pharmacology and Experimental Therapeutics. 9 (4): 231–240. 
  • Ball, Christine M.; Westhorpe, Rod N. (2004). "Local Anaesthesia after Cocaine". Anaesthesia and Intensive Care. 32 (2): 157. PMID 15957711.