The city was in the Athenian alliance in 405BC
Under the Seleucids, Amyzon was one of the cities in the Chrysaorian League of Carian cities that lasted at least until 203 BCE, when Antiochus III confirmed the privileges of Amyzon. The League had a form of reciprocal citizenship whereby a citizen of a member city was entitled to certain rights and privileges in any other member city.
The city was dismissed by Strabo as a mere peripolion ('suburb' or 'township') of Alabanda; Amyzon was mentioned by Pliny, Ptolemy and Hierocles. In the wars among the successors of Alexander, in the 3rd century BCE, the city allied with the less immediately threatening power, first with the Ptolemies, then with the Seleucids. In the second city it concluded an alliance with Heracleia under Latmos. On one occasion it sent a delegation to the oracle of Apollo at Clarus. The few coins identified as from the mint at Amyzon are Hellenistic and Imperial Roman.
A stretch of the city wall stands 6 m high (in fact, the terrace wall of the shrine); inside it are a few ruined and unidentifiable buildings, as well as a row of a dozen large vaulted underground chambers, apparently storerooms. There are also Byzantine structures. Outside the city a series of ruined terraces mark the site of the Doric temple of Artemis, which dates from the time of the Hecatomnids: an architrave block has been found bearing a dedication by Idrieus. Numerous other inscriptions abound.
- Philetus fl451
Titular Roman Bishops
- Jean Baptiste Gillis (3 Aug 1729 Appointed – 1 Dec 1736 Died) 
- Charles Alexandre d'Arberg et de Valengin (31 Aug 1767 Appointed – 19 Dec 1785 Confirmed, Bishop of Ypres (Ieper))
- Godefroid Philippe Joseph de La Porte, (29 Nov 1790 Appointed – 9 Aug 1796 Succeeded, Archbishop of Naxos)
- Miguel Joaquín Matías Suárez, (20 Dec 1802 Appointed – 2 May 1831 Died)
- Franz Großmann (Grossmann) (17 Jun 1844 Appointed – 5 May 1852 Died)
- Ireneus Frederic Baraga (29 Jul 1853 Appointed – 9 Jan 1857 Appointed, Bishop of Sault Sainte Marie, Michigan)
- Józef Twarowski (3 Aug 1857 Appointed – 19 Jan 1868 Died)
- Ildefonso Giovanni Battista Borgna, (24 May 1871 Appointed – 14 Dec 1886 Appointed, Titular Archbishop of Marcianopolis)
- Heinrich Feiten (20 Sep 1887 Appointed – 17 Feb 1892 Died)
- Ignacio Ibáñez, (4 May 1893 Appointed – 14 Oct 1893 Died)
- Pio Gaetano Secondo Stella (22 Dec 1893 Appointed – 21 Sep 1927 Died)
- Gabriele Perlo, (22 Dec 1927 Appointed – 26 Sep 1948 Died)
- Charles Dauvin, (9 Dec 1948 Appointed – 28 Dec 1948 Died)
- Baltasar Álvarez Restrepo † (7 May 1949 Appointed – 18 Dec 1952 Appointed, Bishop of Pereira)
- Luigi Cicuttini (6 Apr 1953 Appointed – 30 Nov 1956 Appointed, Bishop of Città di Castello) 
- Antonin Fishta, (17 Dec 1956 Appointed – 12 Jan 1980 Died) 
- George Ewart Bean: Amyzon (Mazın Kalesi) Turkey. In: Richard Stillwell u. a. (Hrsg.): The Princeton Encyclopedia of Classical Sites. Princeton University Press, Princeton, N.J. 1976, ISBN 0-691-03542-3.
- Gernot Lang: Klassische antike Stätten Anatoliens. BoD, 2003, ISBN 3833000686, p 88–89.
- Louis und Jeanne Robert: Fouilles d'Amyzon en Carie. Tome 1. Exploration, histoire, monnaies et inscriptions. de Boccard, Paris 1983.
- Mogens Herman Hansen & Thomas Heine Nielsen, Caria, in An inventory of archaic and classical poleis, New York, (Oxford University Press, 2004), p. 1111–1112, ISBN 0-19-814099-1.
- J. Ma, Antiochos III and the Cities of Western Asia Minor, :175.
- "Hazlitt, The Classical Gazetteer, s.v. "Chrysaorium"". p. 109. Archived from the original on 2007-03-05. Retrieved 2016-03-30.
- María Marta González González, Cartas de la cancillería helenística (II) en la revista Memorias de historia antigua, ISSN 0210-2943, Nº 11-12, 1990–1991, págs. 127-146 (p.129)
- Strabo, 658.
- The Princeton Encyclopedia of Classical Sites: s.v. "Amyzon".
- See the Bagadates who was a neokoros, at the article Bagadates I.
- Louis Robert, with Jeanne Robert, Fouilles d'Amyzon en Carie I, (Paris: De Boccard) 1983.
- Annuario Pontificio 2013 (Libreria Editrice Vaticana 2013 ISBN 978-88-209-9070-1), p. 831
- Rosemary Morris, Monks and Laymen in Byzantium, 843-1118(Cambridge University Press, 2002)
- Henry Mourice, A Defence of Diocesan Episcopacy, in answer to a book of Mr D. Clarkson ... entituled"Primitive Episcopacy.".(1691)
- David Clarkson, Primitive Episcopacy, evincing from Scripture and ancient records, that a bishop in the Apostles times, and for the space of the first three centuries of the Gospel-Church, was no more than a pastor to one single church or congregation, etc. [With a prefatory epistle by Isaac Chauncy].(Nath. Ponder, 1688)
- Bingham, J.; Bingham, R. (1834). Origines ecclesiasticæ; or, The antiquities of the Christian church, and other works. To which are now added, several sermons. p. 334. Retrieved 2016-03-30.
- Joseph Bingham, Origines ecclesiasticæ; or, The antiquities of the Christian church, and other works. To which are now added, several sermons (Joseph Bingham, 1834) p 334
- Robert Knaplock, The Works, Volume 1 (Robert Knaplock, 1726)p834
- Authoritative Christianity. The third world council ... which was held A.D. 431.
- Amyzona at catholic-hierarchy.org.
- Amyzon at GCatholc.org.
- Le Petit Episcopologe, Issue 188, Number 15,318