His top hits were Hameno Nisi (Lost Island), To Koutsouraki (Little Log), Kiklopaki (Little Cyclops) and Oso Girizei i Gi (As Long As The Earth Turns Around). In 1991 Greece participated in the Eurovision Song Contest with his song Anixi sung by Sophia Vossou (Greek: Σοφία Βόσσου), finishing in 13th place. An album with the same title was released the same year.
During the 1990s, Mikroutsikos presented the famous TV game show To Megalo Pazari (The Great Bazaar - Greek version of Let's Make a Deal). By moving from Mega Channel to ANT1 he was the first to introduce reality shows to the Greek public. His shows have been criticised by many, despite good TV ratings. Mikroutsikos presented the first and second series of the famous reality show Big Brother on the ANT1 channel. He also presented ANT1's music academy Fame Story.
Mikroutsikos moved to Alpha TV where he presented the reality show Apo Kardias (By My Heart). The show was banned by the Greek authorities after an episode in which a woman accused her husband of forcing her to agree to bestiality, specifically sexual acts with their dog. Mikroutsikos defended himself by saying that all the things presented through his popular show were pieces of the puzzle of our life and by closing our eyes we just ignore the problem. Mikroutsikos was nicknamed "realitaras" (reality trump).
Mikroutsikos has been married three times, with Maria Dimitriadi, trainer Foteini Georganta and TV presenter Dimitra Roubessi. He also had a long-term relationship with singer Sophia Vossou. Mikroutsikos has a son, Stergios, from his first marriage with Maria Dimitriadi. He is the brother of Thanos Mikroutsikos. Mikroutsikos, the son of a mathematician, has a degree in mathematics himself. As a youngster, he was a member of the Revolutionary Communist Movement of Greece.
- "Οι Πολλές Ζωές του Ανδρέα Μικρούτσικου | θοδωρής γεωργακόπουλος". www.georgakopoulos.org (in Greek). Retrieved 2015-07-13.
- "Big brother goes Greek". GreeceNow. Archived from the original on 25 May 2006.
- Kritsiolis, Tassos (28 April 2015). ""Αφιερωμένο εξαιρετικά": Η Ελλάδα στη EUROVISION (1991-1995)". musiccorner.gr. Retrieved 19 July 2015.
- "Αντρέας Μικρούτσικος Discography at Discogs" (in Greek). Discogs.gr. Retrieved 19 July 2015.
- "20 Χρόνια ΑΝΤ1 (Συλλεκτικό Αφιέρωμα)" (in Greek). tvnea.com. 30 December 2009. Retrieved 19 July 2015.
- "Ανδρέας Μικρούτσικος" (in Greek). peoplegreece.com. Retrieved 19 July 2015.
- "Οριστική διακοπή της εκπομπής "Από καρδιάς" του Ανδ.Μικρούτσικου" (in Greek). in.gr. 13 June 2006. Retrieved 19 July 2015.
- "Ανδρέας Μικρούτσικος: Η ζωή του ένα παιχνίδι ντόμινο&: Η απομόνωση τα κιλά και η επιστροφή!!!" (in Greek). gossip-tv.gr. 12 October 2012. Retrieved 19 July 2015.
- "Μαρία Δημητριάδη: Νικήθηκε από μία σπάνια ασθένεια" (in Greek). madata.gr. 8 January 2009. Retrieved 19 July 2015.
- "Κουφέτα να γίνεται: Οι ελληνικοί γάμοι που άφησαν εποχή" (in Greek). MYlady.gr. Retrieved 19 July 2015.
- "Η απάντηση της Δήμητρας στον Αντρέα !" (in Greek). TL!fe. 20 May 2010. Retrieved 19 July 2015.
- "Σοφία Βόσσου: γιατί δεν έχει καμία επαφή με τον Ανδρέα Μικρούτσικο [video]" (in Greek). Fimes.gr. 31 March 2014. Retrieved 19 July 2015.
- "Στέργιος Μικρούτσικος: Μιλάει για τον θάνατο της μητέρας του και τον πατέρα του, Ανδρέα!" (in Greek). TL!fe. 15 January 2015. Retrieved 19 July 2015.
- Papaleonardos, Chris (January 8, 2009). "Mourning Maria Dimitriadi". Counterpunch. Retrieved 1 July 2015.
- "Γιατί έγινε η ζωή του σαν τα reality που ο ίδιος παρουσίαζε". Espresso. 24 October 2008. Retrieved 19 July 2015.