Tiller was signed by the San Diego Chargers to their practice squad on September 25, 2013, but was released on September 28, 2013. Tiller was re-signed to the Chargers' practice squad on October 1, 2013. On November 18, 2013, he was released by the Chargers.
Tiller was signed to the practice squad of the San Francisco 49ers on October 18, 2014. He was cut by the 49ers in order for the 49ers to make their 53-man roster. He was then signed to the 49ers' practice squad on September 6, 2015. In the middle of the season he was signed to the 53-man roster and played 2 games alternating snaps with Jordan Devey.