Ang Mo Kio Bus Depot (SBS Transit) is an SBS Transit East District bus depot located in Yio Chu Kang, Singapore. This bus depot is also the starting point for Service 45, Service 128 (AM Peak), Townlink 265 and Townlink 268. As of November 2014, the total fleet is 621 buses.
Ang Mo Kio Bus Depot started operations in 1978, replacing the Paya Lebar Bus Service's Paya Lebar Depot before it relocated to Ang Mo Kio. The old depot was replaced by SMRT TrainsKim Chuan Depot. Service 169 had been the mainstay with Atlanteans together with all services until 1983. On 25 March 1998, several buses were destroyed in a fire from service 143. On 7 March 2010, several buses were destroyed in a fire from service 25 and the buses were deregistrered by 2 November 2010.