Extranodal NK/T-cell lymphoma, nasal type which was known as angiocentric lymphoma in the REAL classification, and also as nasal-type NK lymphoma,NK/T-cell lymphoma, and polymorphic/malignant midline reticulosis is a cutaneous condition which in Korea is reported to be the most common form of cutaneous lymphoma after mycosis fungoides.:739
The NCCN guidelines recommend either high dose radiotherapy alone for stage I without high risk features, or concurrent chemoradiotherapy for stage I and II with either of two regimens. L-asparaginase containing regimens have been used in advanced stage disease.
^Kim, S. J.; Kim, K; Kim, B. S.; Kim, C. Y.; Suh, C; Huh, J; Lee, S. W.; Kim, J. S.; Cho, J; Lee, G. W.; Kang, K. M.; Eom, H. S.; Pyo, H. R.; Ahn, Y. C.; Ko, Y. H.; Kim, W. S. (2009). "Phase II trial of concurrent radiation and weekly cisplatin followed by VIPD chemotherapy in newly diagnosed, stage IE to IIE, nasal, extranodal NK/T-Cell Lymphoma: Consortium for Improving Survival of Lymphoma study". Journal of Clinical Oncology27 (35): 6027–32. doi:10.1200/JCO.2009.23.8592. PMID19884539.
^Yamaguchi, M; Tobinai, K; Oguchi, M; Ishizuka, N; Kobayashi, Y; Isobe, Y; Ishizawa, K; Maseki, N; Itoh, K; Usui, N; Wasada, I; Kinoshita, T; Ohshima, K; Matsuno, Y; Terauchi, T; Nawano, S; Ishikura, S; Kagami, Y; Hotta, T; Oshimi, K (2009). "Phase I/II study of concurrent chemoradiotherapy for localized nasal natural killer/T-cell lymphoma: Japan Clinical Oncology Group Study JCOG0211". Journal of Clinical Oncology27 (33): 5594–600. doi:10.1200/JCO.2009.23.8295. PMID19805668.